TSPY3 [The Human Chemical-Genetic Interaction Map Project]

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======= TSPY3 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: TSPY3
  * **<color #00a2e8>Official Name</color>**: testis specific protein Y-linked 3
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=728137|728137]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P0CV98|P0CV98]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TSPY3&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TSPY3|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Unknown. May be involved in sperm differentiation and proliferation (By similarity). {ECO:0000250}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|NAP|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|gonadal mesoderm development|
|nucleosome assembly|
|mesoderm development|
|chromatin assembly|
|chromatin assembly or disassembly|
|nucleosome organization|
|DNA packaging|
|protein-DNA complex assembly|
|gonad development|
|development of primary sexual characteristics|
|mesenchyme development|
|protein-DNA complex subunit organization|
|sex differentiation|
|DNA conformation change|
|reproductive structure development|
|reproductive system development|
|spermatogenesis|
|male gamete generation|
|developmental process involved in reproduction|
|gamete generation|
|chromatin organization|
|multicellular organismal reproductive process|
|sexual reproduction|
|cellular protein-containing complex assembly|
|multicellular organism reproduction|
|multi-organism reproductive process|
|chromosome organization|
|reproductive process|
|reproduction|
|protein-containing complex assembly|
|tissue development|
|protein-containing complex subunit organization|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 56
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -7.68 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TSPY3 Expression in NALM6 Cells: -7.68'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>