ZNF385C [The Human Chemical-Genetic Interaction Map Project]

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======= ZNF385C =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ZNF385C
  * **<color #00a2e8>Official Name</color>**: zinc finger protein 385C
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=201181|201181]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q66K41|Q66K41]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=ZNF385C&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20ZNF385C|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/620982|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|zf-met|
|zf-C2H2 jaz|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|nucleic acid binding|
|zinc ion binding|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp116|AICAR 240μM R03 exp116]]|-1.93|
|[[:results:exp495|IWR1 50μM R08 exp495]]|-1.81|
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|-1.78|
|[[:results:exp409|THZ531 0.11μM R07 exp409]]|-1.72|
|[[:results:exp283|Glyphosate 1000μM R06 exp283]]|1.72|
|[[:results:exp198|Etoposide 0.1μM R05 exp198]]|1.74|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|1.77|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 12436
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 2.3 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='ZNF385C Expression in NALM6 Cells: 2.3'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>