UM131593 0.2μM R03 exp106 [The Human Chemical-Genetic Interaction Map Project]

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====== UM131593 0.2μM R03 exp106 ======
==== Mechanism of Action ====
Unknown
  * **<color #00a2e8>Class / Subclass 1:</color>** Uncharacterized Mechanism / Chemical Screen Hit




==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Compound References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%N/A%%
    * **<color #00a2e8>Synonyms:</color>** N/A
    * **<color #00a2e8>CAS #:</color>** N/A
    * **<color #00a2e8>PubChem CID:</color>** N/A
    * **<color #00a2e8>IUPAC:</color>** %%N/A%%
    * **<color #00a2e8>INCHI Name:</color>** N/A
    * **<color #00a2e8>INCHI Key:</color>** N/A
    * **<color #00a2e8>Molecular Weight:</color>** 381.45
    * **<color #00a2e8>Canonical SMILES:</color>** N/A
    * **<color #00a2e8>Isomeric SMILES:</color>** N/A
    * **<color #00a2e8>Molecular Formula:</color>** C21H19NO4S
{{:chemogenomics:structures:chem-0038.svg?nolink}}
</panel>


<panel title='Compound Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** In house - University of Montreal - Chemistry Platform
    * **<color #00a2e8>Catalog #:</color>** N/A
    * **<color #00a2e8>Lot #:</color>** IRIC-004 / sj2182-084 / Batch #01
</panel>


<panel title='Compound Characterization' collapsed='true'>
Characterization data not available.
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** UM0131593
    * **<color #00a2e8>Min:</color>** 0.7950; **<color #00a2e8>Max:</color>** 83.0421
{{:chemogenomics:dose_response:dr_140.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |N/A    |
| IC20  |0.0217    |
| IC30  |0.0436    |
| IC40  |0.0772    |
| IC50  |0.1304    |
| IC60  |N/A    |
| IC70  |N/A    |
| IC80  |N/A    |
| IC90  |N/A    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 03
    * **<color #00a2e8>Dose</color>**: 200nM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 1.2
    * **<color #00a2e8>Numbers of reads</color>**: 12428553


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|8/138|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/UM131593_0.2uM_Round-3_exp106.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="default" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='UM131593 0.2μM R03 exp106'>
{{:chemogenomics:cranks_plots:exp106.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:P:PDS5B|PDS5B]]|-3.20|<0.01|
|[[:human_genes:P:PCGF1|PCGF1]]|-3.19|<0.01|
|[[:human_genes:I:ITFG2|ITFG2]]|-2.86|0.02|
|[[:human_genes:G:GNL2|GNL2]]|-2.84|0.03|
|[[:human_genes:R:RPL18|RPL18]]|-2.74|0.34|
|[[:human_genes:L:LRRC8A|LRRC8A]]|-2.74|0.02|
|[[:human_genes:E:ENO2|ENO2]]|-2.61|0.05|
|[[:human_genes:T:TUBGCP2|TUBGCP2]]|-2.60|0.05|
|[[:human_genes:W:WAPAL|WAPAL]]|-2.58|0.11|
|[[:human_genes:K:KATNA1|KATNA1]]|-2.55|0.05|
|[[:human_genes:H:HEXIM1|HEXIM1]]|-2.51|0.05|
|[[:human_genes:D:DLGAP5|DLGAP5]]|-2.49|0.05|
|[[:human_genes:M:MSI2|MSI2]]|-2.46|0.05|
|[[:human_genes:C:CENPW|CENPW]]|-2.37|0.12|
|[[:human_genes:S:SKIV2L2|SKIV2L2]]|-2.36|0.22|
|[[:human_genes:P:PSTK|PSTK]]|-2.36|0.08|
|[[:human_genes:F:FAM120A|FAM120A]]|-2.34|0.08|
|[[:human_genes:T:TNRC6C|TNRC6C]]|-2.24|0.15|
|[[:human_genes:R:RING1|RING1]]|-2.24|0.15|
|[[:human_genes:E:ESCO2|ESCO2]]|-2.24|0.12|
|[[:human_genes:Z:ZNF292|ZNF292]]|-2.23|0.12|
|[[:human_genes:H:HNRNPU|HNRNPU]]|-2.21|0.12|
|[[:human_genes:G:GPBP1|GPBP1]]|-2.20|0.16|
|[[:human_genes:C:C12orf43|C12orf43]]|-2.20|0.12|
|[[:human_genes:Y:YPEL5|YPEL5]]|-2.19|0.12|
|[[:human_genes:A:ACBD3|ACBD3]]|-2.19|0.22|
|[[:human_genes:N:NPIPA7|NPIPA7]]|-2.17|0.12|
|[[:human_genes:Q:QRICH1|QRICH1]]|-2.17|0.23|
|[[:human_genes:G:GAK|GAK]]|-2.16|0.12|
|[[:human_genes:N:NPIPA8|NPIPA8]]|-2.16|0.12|
|[[:human_genes:R:ROMO1|ROMO1]]|3.45|<0.01|
|[[:human_genes:T:TADA1|TADA1]]|3.48|<0.01|
|[[:human_genes:D:DHX29|DHX29]]|3.49|<0.01|
|[[:human_genes:M:MBTPS2|MBTPS2]]|3.51|<0.01|
|[[:human_genes:T:TAF5L|TAF5L]]|3.54|<0.01|
|[[:human_genes:M:MED13|MED13]]|3.66|<0.01|
|[[:human_genes:A:ALDH18A1|ALDH18A1]]|3.66|<0.01|
|[[:human_genes:P:PFN1|PFN1]]|3.68|<0.01|
|[[:human_genes:A:ARHGAP11B|ARHGAP11B]]|3.74|<0.01|
|[[:human_genes:B:BRPF1|BRPF1]]|3.86|<0.01|
|[[:human_genes:F:FBXO11|FBXO11]]|3.87|<0.01|
|[[:human_genes:D:DDX5|DDX5]]|3.89|<0.01|
|[[:human_genes:S:STK11|STK11]]|3.91|<0.01|
|[[:human_genes:M:MAX|MAX]]|3.98|<0.01|
|[[:human_genes:T:TRIM28|TRIM28]]|4.01|<0.01|
|[[:human_genes:S:SRF|SRF]]|4.02|<0.01|
|[[:human_genes:A:AMBRA1|AMBRA1]]|4.42|<0.01|
|[[:human_genes:P:PRKAR1A|PRKAR1A]]|4.77|<0.01|
|[[:human_genes:T:TP53|TP53]]|5.20|<0.01|
|[[:human_genes:N:NSD1|NSD1]]|5.68|<0.01|
|[[:human_genes:C:CBX3|CBX3]]|5.88|<0.01|
|[[:human_genes:S:SETDB1|SETDB1]]|5.91|<0.01|
|[[:human_genes:I:ID3|ID3]]|5.92|<0.01|
|[[:human_genes:K:KIF2C|KIF2C]]|5.95|<0.01|
|[[:human_genes:T:TMEM161B|TMEM161B]]|6.03|<0.01|
|[[:human_genes:A:ATP1A1|ATP1A1]]|6.19|<0.01|
|[[:human_genes:A:ATF7IP|ATF7IP]]|6.25|<0.01|
|[[:human_genes:N:NDRG3|NDRG3]]|6.65|<0.01|
|[[:human_genes:A:ATAT1|ATAT1]]|6.67|<0.01|
|[[:human_genes:K:KIF18B|KIF18B]]|7.08|<0.01|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp59|UMK57 1μM R01 exp59]]|0.14|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp108|Vinblastine 0.2μM R03 exp108]]|0.051|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|0.172|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|0.133|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|0.106|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|0.105|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|0.096|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp34|Rotenone 20μM R00 exp34]]|0.091|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.09|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.09|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.085|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|0.084|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|0.08|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.079|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp350|Deferoxamine 11μM R07 exp350]]|0.077|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp211|AICAR 240μM R05 exp211]]|0.077|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.076|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.074|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp517|Quercetin 20μM R08 exp517]]|0.071|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|0.07|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp199|Etoposide 0.3μM R05 exp199]]|0.068|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp228|Demecolcine 0.03μM R05 exp228]]|0.068|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|0.067|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp67|BVD-523 15μM R02 exp67]]|0.066|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|0.066|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp290|LLY-283 2.6μM R06 exp290]]|0.064|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|0.063|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp135|MS023 7μM R03 exp135]]|0.062|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp103|Taxol 0.004μM R03 exp103]]|0.062|<button type="primary" size="small" modal="29">View</button>|
|[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.061|<button type="primary" size="small" modal="30">View</button>|
|[[:results:exp539|42°C R08 exp539]]|0.061|<button type="primary" size="small" modal="31">View</button>|
|[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|0.06|<button type="primary" size="small" modal="32">View</button>|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.059|<button type="primary" size="small" modal="33">View</button>|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|0.057|<button type="primary" size="small" modal="34">View</button>|
|[[:results:exp179|Combretastatin A4 0.002 to 0.003μM day4 R04 exp179]]|0.055|<button type="primary" size="small" modal="35">View</button>|
|[[:results:exp499|LY2090314 0.003μM R08 exp499]]|0.054|<button type="primary" size="small" modal="36">View</button>|
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|0.053|<button type="primary" size="small" modal="37">View</button>|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.053|<button type="primary" size="small" modal="38">View</button>|
|[[:results:exp96|BI-2536 0.02μM R03 exp96]]|0.052|<button type="primary" size="small" modal="39">View</button>|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|0.052|<button type="primary" size="small" modal="40">View</button>|
|[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|0.052|<button type="primary" size="small" modal="41">View</button>|
|[[:results:exp22|MLN-4924 2μM R00 exp22]]|0.051|<button type="primary" size="small" modal="42">View</button>|
</modal>


<modal id="1" size="lg" title="UM131593 0.2μM R03 exp106  vs  UMK57 1μM R01 exp59">
{{:chemogenomics:comparison_plots:exp106_vs_exp59.png?nolink |}}
</modal>

<modal id="2" size="lg" title="UM131593 0.2μM R03 exp106  vs  Vinblastine 0.2μM R03 exp108">
{{:chemogenomics:comparison_plots:exp106_vs_exp108.png?nolink |}}
</modal>

<modal id="3" size="lg" title="BML-284 0.09μM R08 exp460  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp460.png?nolink |}}
</modal>

<modal id="4" size="lg" title="Mdivi-1 15μM R05 exp217  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp217.png?nolink |}}
</modal>

<modal id="5" size="lg" title="5-Fluorouracil 20μM R00 exp2  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp2.png?nolink |}}
</modal>

<modal id="6" size="lg" title="Actinomycin-D 0.001μM R00 exp3  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp3.png?nolink |}}
</modal>

<modal id="7" size="lg" title="3-Bromopyruvate 7μM R04 exp175  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp175.png?nolink |}}
</modal>

<modal id="8" size="lg" title="Rotenone 20μM R00 exp34  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp34.png?nolink |}}
</modal>

<modal id="9" size="lg" title="Doxorubicin 0.02μM R08 exp478  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp478.png?nolink |}}
</modal>

<modal id="10" size="lg" title="Mitomycin-C 0.06μM R08 exp503  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp503.png?nolink |}}
</modal>

<modal id="11" size="lg" title="CI-1040 9.5μM R08 exp472  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp472.png?nolink |}}
</modal>

<modal id="12" size="lg" title="2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp312.png?nolink |}}
</modal>

<modal id="13" size="lg" title="Bleomycin 5μM R08 exp459  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp459.png?nolink |}}
</modal>

<modal id="14" size="lg" title="Aphidicolin 0.4μM R08 exp440  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp440.png?nolink |}}
</modal>

<modal id="15" size="lg" title="Deferoxamine 11μM R07 exp350  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp350.png?nolink |}}
</modal>

<modal id="16" size="lg" title="AICAR 240μM R05 exp211  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp211.png?nolink |}}
</modal>

<modal id="17" size="lg" title="Atovaquone 15μM R08 exp451  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp451.png?nolink |}}
</modal>

<modal id="18" size="lg" title="RO-3307 4.7μM R02 exp80  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp80.png?nolink |}}
</modal>

<modal id="19" size="lg" title="Quercetin 20μM R08 exp517  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp517.png?nolink |}}
</modal>

<modal id="20" size="lg" title="Pimelic-diphenylamide-106 5μM R00 exp28  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp28.png?nolink |}}
</modal>

<modal id="21" size="lg" title="Etoposide 0.3μM R05 exp199  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp199.png?nolink |}}
</modal>

<modal id="22" size="lg" title="Demecolcine 0.03μM R05 exp228  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp228.png?nolink |}}
</modal>

<modal id="23" size="lg" title="LY2090314 0.003μM R08 exp500 no dilution day6  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp500.png?nolink |}}
</modal>

<modal id="24" size="lg" title="BVD-523 15μM R02 exp67  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp67.png?nolink |}}
</modal>

<modal id="25" size="lg" title="PU-H71 1μM R08 exp515  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp515.png?nolink |}}
</modal>

<modal id="26" size="lg" title="LLY-283 2.6μM R06 exp290  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp290.png?nolink |}}
</modal>

<modal id="27" size="lg" title="Colchicine 0.009μM R05 exp215  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp215.png?nolink |}}
</modal>

<modal id="28" size="lg" title="MS023 7μM R03 exp135  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp135.png?nolink |}}
</modal>

<modal id="29" size="lg" title="Taxol 0.004μM R03 exp103  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp103_vs_exp106.png?nolink |}}
</modal>

<modal id="30" size="lg" title="JQ1 0.8μM R08 exp435  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp435.png?nolink |}}
</modal>

<modal id="31" size="lg" title="42°C R08 exp539  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp539.png?nolink |}}
</modal>

<modal id="32" size="lg" title="Ammonium tetrathiomolybdate 10μM R08 exp448  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp448.png?nolink |}}
</modal>

<modal id="33" size="lg" title="Benzoate 20000μM R08 exp456  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp456.png?nolink |}}
</modal>

<modal id="34" size="lg" title="SNS-032 15μM R08 exp443  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp443.png?nolink |}}
</modal>

<modal id="35" size="lg" title="Combretastatin A4 0.002 to 0.003μM day4 R04 exp179  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp179.png?nolink |}}
</modal>

<modal id="36" size="lg" title="LY2090314 0.003μM R08 exp499  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp499.png?nolink |}}
</modal>

<modal id="37" size="lg" title="THZ1 0.06μM R08 exp531  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp531.png?nolink |}}
</modal>

<modal id="38" size="lg" title="Artemisinin 50μM R08 exp450  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp450.png?nolink |}}
</modal>

<modal id="39" size="lg" title="BI-2536 0.02μM R03 exp96  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp96.png?nolink |}}
</modal>

<modal id="40" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp529.png?nolink |}}
</modal>

<modal id="41" size="lg" title="GSK461364A 0.1μM R03 exp126  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp126.png?nolink |}}
</modal>

<modal id="42" size="lg" title="MLN-4924 2μM R00 exp22  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp22.png?nolink |}}
</modal>



<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">No GO term hits below threshold. (FDR <0.05)</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">
^GO Term^Fold Change^Genes^
|positive regulation of DNA methylation-dependent heterochromatin formation|165.79|ATF7IP,SETDB1,TRIM28|
|positive regulation of chromatin organization|127.53|ATF7IP,SETDB1,TRIM28|
|regulation of DNA methylation-dependent heterochromatin formation|97.52|ATF7IP,SETDB1,TRIM28|
|regulation of heterochromatin formation|72.08|ATF7IP,SETDB1,TRIM28|
|regulation of heterochromatin organization|72.08|ATF7IP,SETDB1,TRIM28|
|promoter-specific chromatin binding|34.01|SETDB1,TP53,TRIM28,DDX5|
|regulation of transcription initiation by RNA polymerase II|31.13|ATF7IP,TP53,SRF,MED13|
|regulation of DNA-templated transcription initiation|27.98|ATF7IP,TP53,SRF,MED13|
|positive regulation of cellular component biogenesis|8.95|ATAT1,ATF7IP,SETDB1,TP53,AMBRA1,SRF,TRIM28,PFN1|
|DNA-binding transcription factor binding|8.23|ID3,NSD1,TP53,SRF,MAX,DDX5,MED13|
|transcription factor binding|7.51|ID3,CBX3,NSD1,TP53,SRF,MAX,DDX5,MED13|
|transferase complex|6.01|PRKAR1A,AMBRA1,MAX,STK11,FBXO11,BRPF1,MED13,TAF5L,TADA1|
</modal>