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Ask your administrator if you think this is wrong. ====== SNS-032 15μM R08 exp443 ====== ==== Mechanism of Action ==== Inhibits CDK2, CDK7, CDK9 * **<color #00a2e8>Class / Subclass 1:</color>** Cell Cycle / Cyclin Dependent Kinase Inhibitor * **<color #00a2e8>Class / Subclass 2:</color>** Signal Transduction / Kinase Inhibitor ==== Technical Notes ==== <accordion collapsed='true'> <panel title='Compound References' collapsed='true'> * **<color #00a2e8>PubChem Name:</color>** %%Sns-032%% * **<color #00a2e8>Synonyms:</color>** BMS-387032 * **<color #00a2e8>CAS #:</color>** 345627-80-7 * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/3025986|3025986]] * **<color #00a2e8>IUPAC:</color>** %%N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide%% * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22) * **<color #00a2e8>INCHI Key:</color>** OUSFTKFNBAZUKL-UHFFFAOYSA-N * **<color #00a2e8>Molecular Weight:</color>** 380.5 * **<color #00a2e8>Canonical SMILES:</color>** CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC3 * **<color #00a2e8>Isomeric SMILES:</color>** N/A * **<color #00a2e8>Molecular Formula:</color>** C17H24N4O2S2 {{:chemogenomics:structures:chem-0239.svg?nolink}} </panel> <panel title='Compound Supplier' collapsed='true'> * **<color #00a2e8>Supplier Name:</color>** Ark Pharm Inc. * **<color #00a2e8>Catalog #:</color>** AK113734 * **<color #00a2e8>Lot #:</color>** WG0165410-180313001 </panel> <panel title='Compound Characterization' collapsed='true'> * **<color #00a2e8>HRMS (ESI-TOF) m/z:</color>** (M+H)+ Calcd for C17H24N4O2S2 381.14134; found 381.14119 </panel> <panel title='Dose Response Curve' collapsed='true'> * **<color #00a2e8>Platform ID:</color>** SNS-032 * **<color #00a2e8>Min:</color>** -14.2699; **<color #00a2e8>Max:</color>** 96.2471 {{:chemogenomics:dose_response:dr_449.png?nolink&500 |}} \\ \\ \\ \\ |< 300px 100px 200px >| ^ IC ^ Concentration (µM) ^ | IC10 |N/A | | IC20 |17.2802 | | IC30 |19.7073 | | IC40 |22.2581 | | IC50 |25.1188 | | IC60 |N/A | | IC70 |N/A | | IC80 |N/A | | IC90 |N/A | \\ </panel> </accordion> ==== Screen Summary ==== * **<color #00a2e8>Round</color>**: 08 * **<color #00a2e8>Dose</color>**: 15µM * **<color #00a2e8>Days of incubation</color>**: 8 * **<color #00a2e8>Doublings</color>**: -0.3 * **<color #00a2e8>Numbers of reads</color>**: 19448233 ==== Screen Results ==== ^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^ |7/45|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/SNS-032_15uM_Round-8_exp443.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="default" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>| <modal id='ScorePlot' size='lg' title='SNS-032 15μM R08 exp443'> {{:chemogenomics:cranks_plots:exp443.png?nolink}} </modal> <modal id="modal_hits" size="sm" title="Top 30 S/R Genes"> ^Gene^CRANKS Score^FDR^ |[[:human_genes:P:POLR2L|POLR2L]]|-3.54|0.13| |[[:human_genes:A:AURKB|AURKB]]|-3.30|0.09| |[[:human_genes:B:BCL2L1|BCL2L1]]|-3.09|<0.01| |[[:human_genes:N:NRAS|NRAS]]|-3.06|<0.01| |[[:human_genes:A:ATP13A1|ATP13A1]]|-3.03|<0.01| |[[:human_genes:G:GPR107|GPR107]]|-2.93|<0.01| |[[:human_genes:C:CDC73|CDC73]]|-2.77|0.06| |[[:human_genes:C:CDC42|CDC42]]|-2.68|0.03| |[[:human_genes:P:PSMA7|PSMA7]]|-2.64|0.11| |[[:human_genes:R:RNF113A|RNF113A]]|-2.61|0.06| |[[:human_genes:B:BCL2|BCL2]]|-2.55|0.04| |[[:human_genes:P:PPP1R12A|PPP1R12A]]|-2.55|0.04| |[[:human_genes:V:VPS51|VPS51]]|-2.54|0.09| |[[:human_genes:T:TTK|TTK]]|-2.47|0.08| |[[:human_genes:S:SMG7|SMG7]]|-2.43|0.09| |[[:human_genes:F:FHL2|FHL2]]|-2.39|0.07| |[[:human_genes:Z:ZNF737|ZNF737]]|-2.39|0.09| |[[:human_genes:Z:ZFAND5|ZFAND5]]|-2.39|0.07| |[[:human_genes:C:CCDC116|CCDC116]]|-2.37|0.14| |[[:human_genes:P:POLD3|POLD3]]|-2.36|0.54| |[[:human_genes:E:EXOSC1|EXOSC1]]|-2.35|0.10| |[[:human_genes:T:TBC1D3L|TBC1D3L]]|-2.34|0.29| |[[:human_genes:P:POLA1|POLA1]]|-2.34|0.29| |[[:human_genes:W:WSB2|WSB2]]|-2.33|0.08| |[[:human_genes:T:TBC1D3K|TBC1D3K]]|-2.33|0.30| |[[:human_genes:T:TBC1D3E|TBC1D3E]]|-2.32|0.30| |[[:human_genes:T:TBC1D3I|TBC1D3I]]|-2.30|0.31| |[[:human_genes:G:GCLC|GCLC]]|-2.29|0.09| |[[:human_genes:Y:YRDC|YRDC]]|-2.29|0.31| |[[:human_genes:A:ARCN1|ARCN1]]|-2.27|0.12| |[[:human_genes:S:SUZ12|SUZ12]]|2.54|0.01| |[[:human_genes:C:CCDC101|CCDC101]]|2.54|0.01| |[[:human_genes:P:PARL|PARL]]|2.55|0.02| |[[:human_genes:T:TTI2|TTI2]]|2.58|0.02| |[[:human_genes:C:CYCS|CYCS]]|2.61|0.01| |[[:human_genes:M:MLST8|MLST8]]|2.69|<0.01| |[[:human_genes:C:CSNK2B|CSNK2B]]|2.77|0.01| |[[:human_genes:C:C10orf12|C10orf12]]|2.79|0.01| |[[:human_genes:M:MED16|MED16]]|2.80|0.02| |[[:human_genes:K:KCTD5|KCTD5]]|2.81|<0.01| |[[:human_genes:T:TAZ|TAZ]]|2.82|0.06| |[[:human_genes:A:AHCYL1|AHCYL1]]|2.84|<0.01| |[[:human_genes:E:EPRS|EPRS]]|2.86|0.03| |[[:human_genes:F:FBXO11|FBXO11]]|2.87|<0.01| |[[:human_genes:E:EZH2|EZH2]]|2.91|<0.01| |[[:human_genes:H:HCCS|HCCS]]|2.91|0.01| |[[:human_genes:E:ERCC2|ERCC2]]|2.97|0.09| |[[:human_genes:A:ATP2B1|ATP2B1]]|2.99|<0.01| |[[:human_genes:S:STAU1|STAU1]]|3.00|<0.01| |[[:human_genes:T:TTI1|TTI1]]|3.00|<0.01| |[[:human_genes:G:GNB1L|GNB1L]]|3.03|<0.01| |[[:human_genes:P:PHIP|PHIP]]|3.05|<0.01| |[[:human_genes:C:CASP9|CASP9]]|3.33|<0.01| |[[:human_genes:F:FAF2|FAF2]]|3.60|<0.01| |[[:human_genes:G:GMPPB|GMPPB]]|3.62|0.02| |[[:human_genes:M:MARCH5|MARCH5]]|3.63|<0.01| |[[:human_genes:V:VDAC2|VDAC2]]|3.84|<0.01| |[[:human_genes:K:KMT2D|KMT2D]]|4.44|<0.01| |[[:human_genes:A:APAF1|APAF1]]|4.67|<0.01| |[[:human_genes:B:BAK1|BAK1]]|5.47|<0.01| </modal> <modal id="modal_screen_similarity" size="lg" title="Correlated Screens"> ^Screen^Correlation^Plot^ |[[:results:exp531|THZ1 0.06μM R08 exp531]]|0.146|<button type="primary" size="small" modal="1">View</button>| |[[:results:exp527|Tanespimycin 14μM R08 exp527]]|0.077|<button type="primary" size="small" modal="2">View</button>| |[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.075|<button type="primary" size="small" modal="3">View</button>| |[[:results:exp85|UM0129480 7μM R02 exp85]]|0.067|<button type="primary" size="small" modal="4">View</button>| |[[:results:exp108|Vinblastine 0.2μM R03 exp108]]|0.064|<button type="primary" size="small" modal="5">View</button>| |[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|0.06|<button type="primary" size="small" modal="6">View</button>| |[[:results:exp106|UM131593 0.2μM R03 exp106]]|0.057|<button type="primary" size="small" modal="7">View</button>| |[[:results:exp459|Bleomycin 5μM R08 exp459]]|0.127|<button type="primary" size="small" modal="8">View</button>| |[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.117|<button type="primary" size="small" modal="9">View</button>| |[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.117|<button type="primary" size="small" modal="10">View</button>| |[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.109|<button type="primary" size="small" modal="11">View</button>| |[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.108|<button type="primary" size="small" modal="12">View</button>| |[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.103|<button type="primary" size="small" modal="13">View</button>| |[[:results:exp96|BI-2536 0.02μM R03 exp96]]|0.096|<button type="primary" size="small" modal="14">View</button>| |[[:results:exp135|MS023 7μM R03 exp135]]|0.095|<button type="primary" size="small" modal="15">View</button>| |[[:results:exp515|PU-H71 1μM R08 exp515]]|0.094|<button type="primary" size="small" modal="16">View</button>| |[[:results:exp199|Etoposide 0.3μM R05 exp199]]|0.092|<button type="primary" size="small" modal="17">View</button>| |[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|0.092|<button type="primary" size="small" modal="18">View</button>| |[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.092|<button type="primary" size="small" modal="19">View</button>| |[[:results:exp512|Olaparib 4μM R08 exp512]]|0.083|<button type="primary" size="small" modal="20">View</button>| |[[:results:exp34|Rotenone 20μM R00 exp34]]|0.083|<button type="primary" size="small" modal="21">View</button>| |[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|0.081|<button type="primary" size="small" modal="22">View</button>| |[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|0.081|<button type="primary" size="small" modal="23">View</button>| |[[:results:exp474|CR131-b 0.005μM R08 exp474]]|0.079|<button type="primary" size="small" modal="24">View</button>| |[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.077|<button type="primary" size="small" modal="25">View</button>| |[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.076|<button type="primary" size="small" modal="26">View</button>| |[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.076|<button type="primary" size="small" modal="27">View</button>| |[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|0.076|<button type="primary" size="small" modal="28">View</button>| |[[:results:exp116|AICAR 240μM R03 exp116]]|0.075|<button type="primary" size="small" modal="29">View</button>| |[[:results:exp468|CB-5083 0.4μM R08 exp468]]|0.071|<button type="primary" size="small" modal="30">View</button>| |[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|0.071|<button type="primary" size="small" modal="31">View</button>| |[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.071|<button type="primary" size="small" modal="32">View</button>| |[[:results:exp134|MS023 2μM R03 exp134]]|0.068|<button type="primary" size="small" modal="33">View</button>| |[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|0.067|<button type="primary" size="small" modal="34">View</button>| |[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.066|<button type="primary" size="small" modal="35">View</button>| |[[:results:exp22|MLN-4924 2μM R00 exp22]]|0.065|<button type="primary" size="small" modal="36">View</button>| |[[:results:exp19|Etoposide 1μM R00 exp19]]|0.064|<button type="primary" size="small" modal="37">View</button>| |[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|0.064|<button type="primary" size="small" modal="38">View</button>| |[[:results:exp211|AICAR 240μM R05 exp211]]|0.062|<button type="primary" size="small" modal="39">View</button>| |[[:results:exp517|Quercetin 20μM R08 exp517]]|0.06|<button type="primary" size="small" modal="40">View</button>| |[[:results:exp485|GSK626616 14μM R08 exp485]]|0.058|<button type="primary" size="small" modal="41">View</button>| |[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.058|<button type="primary" size="small" modal="42">View</button>| |[[:results:exp502|Milciclib 2μM R08 exp502]]|0.055|<button type="primary" size="small" modal="43">View</button>| |[[:results:exp98|BI-6727 0.04μM R03 exp98]]|0.053|<button type="primary" size="small" modal="44">View</button>| |[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|0.053|<button type="primary" size="small" modal="45">View</button>| |[[:results:exp539|42°C R08 exp539]]|0.052|<button type="primary" size="small" modal="46">View</button>| </modal> <modal id="1" size="lg" title="SNS-032 15μM R08 exp443 vs THZ1 0.06μM R08 exp531"> {{:chemogenomics:comparison_plots:exp443_vs_exp531.png?nolink |}} </modal> <modal id="2" size="lg" title="SNS-032 15μM R08 exp443 vs Tanespimycin 14μM R08 exp527"> {{:chemogenomics:comparison_plots:exp443_vs_exp527.png?nolink |}} </modal> <modal id="3" size="lg" title="SNS-032 15μM R08 exp443 vs Staurosporine 0.02μM R08 exp524"> {{:chemogenomics:comparison_plots:exp443_vs_exp524.png?nolink |}} </modal> <modal id="4" size="lg" title="SNS-032 15μM R08 exp443 vs UM0129480 7μM R02 exp85"> {{:chemogenomics:comparison_plots:exp443_vs_exp85.png?nolink |}} </modal> <modal id="5" size="lg" title="SNS-032 15μM R08 exp443 vs Vinblastine 0.2μM R03 exp108"> {{:chemogenomics:comparison_plots:exp108_vs_exp443.png?nolink |}} </modal> <modal id="6" size="lg" title="SNS-032 15μM R08 exp443 vs Thimerosal 0.85μM R08 exp529"> {{:chemogenomics:comparison_plots:exp443_vs_exp529.png?nolink |}} </modal> <modal id="7" size="lg" title="SNS-032 15μM R08 exp443 vs UM131593 0.2μM R03 exp106"> {{:chemogenomics:comparison_plots:exp106_vs_exp443.png?nolink |}} </modal> <modal id="8" size="lg" title="Bleomycin 5μM R08 exp459 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp459.png?nolink |}} </modal> <modal id="9" size="lg" title="Mitomycin-C 0.06μM R08 exp503 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp503.png?nolink |}} </modal> <modal id="10" size="lg" title="Benzoate 20000μM R08 exp456 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp456.png?nolink |}} </modal> <modal id="11" size="lg" title="Doxorubicin 0.02μM R08 exp478 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp478.png?nolink |}} </modal> <modal id="12" size="lg" title="JQ1 0.8μM R08 exp435 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp435_vs_exp443.png?nolink |}} </modal> <modal id="13" size="lg" title="Atovaquone 15μM R08 exp451 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp451.png?nolink |}} </modal> <modal id="14" size="lg" title="BI-2536 0.02μM R03 exp96 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp96.png?nolink |}} </modal> <modal id="15" size="lg" title="MS023 7μM R03 exp135 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp135_vs_exp443.png?nolink |}} </modal> <modal id="16" size="lg" title="PU-H71 1μM R08 exp515 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp515.png?nolink |}} </modal> <modal id="17" size="lg" title="Etoposide 0.3μM R05 exp199 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp199_vs_exp443.png?nolink |}} </modal> <modal id="18" size="lg" title="5-Fluorouracil 20μM R00 exp2 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp2_vs_exp443.png?nolink |}} </modal> <modal id="19" size="lg" title="Aphidicolin 0.4μM R08 exp440 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp440_vs_exp443.png?nolink |}} </modal> <modal id="20" size="lg" title="Olaparib 4μM R08 exp512 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp512.png?nolink |}} </modal> <modal id="21" size="lg" title="Rotenone 20μM R00 exp34 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp34_vs_exp443.png?nolink |}} </modal> <modal id="22" size="lg" title="6-Thio-2-deoxyguanosine 2μM R06 exp259 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp259_vs_exp443.png?nolink |}} </modal> <modal id="23" size="lg" title="GSK461364A 0.1μM R03 exp126 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp126_vs_exp443.png?nolink |}} </modal> <modal id="24" size="lg" title="CR131-b 0.005μM R08 exp474 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp474.png?nolink |}} </modal> <modal id="25" size="lg" title="CI-1040 9.5μM R08 exp472 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp472.png?nolink |}} </modal> <modal id="26" size="lg" title="RO-3307 4.7μM R02 exp80 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp80.png?nolink |}} </modal> <modal id="27" size="lg" title="Hippuristanol 0.12μM R08 exp488 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp488.png?nolink |}} </modal> <modal id="28" size="lg" title="Ammonium tetrathiomolybdate 10μM R08 exp448 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp448.png?nolink |}} </modal> <modal id="29" size="lg" title="AICAR 240μM R03 exp116 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp116_vs_exp443.png?nolink |}} </modal> <modal id="30" size="lg" title="CB-5083 0.4μM R08 exp468 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp468.png?nolink |}} </modal> <modal id="31" size="lg" title="Actinomycin-D 0.001μM R00 exp3 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp3_vs_exp443.png?nolink |}} </modal> <modal id="32" size="lg" title="Hippuristanol 0.12μM R08 exp489 no dilution day6 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp489.png?nolink |}} </modal> <modal id="33" size="lg" title="MS023 2μM R03 exp134 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp134_vs_exp443.png?nolink |}} </modal> <modal id="34" size="lg" title="Pimelic-diphenylamide-106 5μM R00 exp28 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp28_vs_exp443.png?nolink |}} </modal> <modal id="35" size="lg" title="Artemisinin 50μM R08 exp450 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp450.png?nolink |}} </modal> <modal id="36" size="lg" title="MLN-4924 2μM R00 exp22 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp22_vs_exp443.png?nolink |}} </modal> <modal id="37" size="lg" title="Etoposide 1μM R00 exp19 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp19_vs_exp443.png?nolink |}} </modal> <modal id="38" size="lg" title="Hinokiflavone 12μM R08 exp487 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp487.png?nolink |}} </modal> <modal id="39" size="lg" title="AICAR 240μM R05 exp211 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp211_vs_exp443.png?nolink |}} </modal> <modal id="40" size="lg" title="Quercetin 20μM R08 exp517 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp517.png?nolink |}} </modal> <modal id="41" size="lg" title="GSK626616 14μM R08 exp485 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp485.png?nolink |}} </modal> <modal id="42" size="lg" title="Dorsomorphin 5μM R07 exp357 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp357_vs_exp443.png?nolink |}} </modal> <modal id="43" size="lg" title="Milciclib 2μM R08 exp502 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp502.png?nolink |}} </modal> <modal id="44" size="lg" title="BI-6727 0.04μM R03 exp98 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp98.png?nolink |}} </modal> <modal id="45" size="lg" title="2-Deoxy-D-glucose 800μM R05 exp214 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp214_vs_exp443.png?nolink |}} </modal> <modal id="46" size="lg" title="42°C R08 exp539 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp539.png?nolink |}} </modal> <modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">No GO term hits below threshold. (FDR <0.05)</modal> <modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms"> ^GO Term^Fold Change^Genes^ |apoptosome|552.30|APAF1,CASP9| |activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|331.38|APAF1,CASP9,CYCS| </modal> Last modified: 2026/01/15 21:36by 127.0.0.1