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Ask your administrator if you think this is wrong. ====== Bleomycin 5μM R08 exp459 ====== ==== Mechanism of Action ==== Induces DNA strand breaks, possibly by iron chelation and ROS generation, or generation of alkali-labile lesions * **<color #00a2e8>Class / Subclass 1:</color>** DNA Damage, Repair and Replication / Clastogen ==== Technical Notes ==== <accordion collapsed='true'> <panel title='Compound References' collapsed='true'> * **<color #00a2e8>PubChem Name:</color>** %%Bleomycin sulfate%% * **<color #00a2e8>Synonyms:</color>** N/A * **<color #00a2e8>CAS #:</color>** 9041-93-4 * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/72466|72466]] * **<color #00a2e8>IUPAC:</color>** %%3-[[2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2R,3S,4S,5R,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium;hydrogen sulfate%% * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21?,22?,23?,24?,25?,29-,30+,34?,35?,36?,37+,38+,39-,40-,41?,42-,43-,53+,54-;/m0./s1 * **<color #00a2e8>INCHI Key:</color>** WUIABRMSWOKTOF-OCBSMOPSSA-N * **<color #00a2e8>Molecular Weight:</color>** 1512.6 * **<color #00a2e8>Canonical SMILES:</color>** CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-] * **<color #00a2e8>Isomeric SMILES:</color>** CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-] * **<color #00a2e8>Molecular Formula:</color>** C55H85N17O25S4 {{:chemogenomics:structures:chem-0269.svg?nolink}} </panel> <panel title='Compound Supplier' collapsed='true'> * **<color #00a2e8>Supplier Name:</color>** Med Chem Express * **<color #00a2e8>Catalog #:</color>** HY-17565 * **<color #00a2e8>Lot #:</color>** 27306 </panel> <panel title='Compound Characterization' collapsed='true'> * **<color #00a2e8>HRMS (ESI-TOF) m/z:</color>** (M)+ Calcd for C55H84N17O21S3 1414.51898; found 1414.51692 </panel> <panel title='Dose Response Curve' collapsed='true'> * **<color #00a2e8>Platform ID:</color>** Bleomycin * **<color #00a2e8>Min:</color>** -9.4082; **<color #00a2e8>Max:</color>** 78.5072 {{:chemogenomics:dose_response:dr_505.png?nolink&500 |}} \\ \\ \\ \\ |< 300px 100px 200px >| ^ IC ^ Concentration (µM) ^ | IC10 |0.8983 | | IC20 |1.7420 | | IC30 |2.7040 | | IC40 |3.8790 | | IC50 |5.4010 | | IC60 |7.5210 | | IC70 |10.7900 | | IC80 |16.7500 | | IC90 |32.4800 | \\ </panel> </accordion> ==== Screen Summary ==== * **<color #00a2e8>Round</color>**: 08 * **<color #00a2e8>Dose</color>**: 5µM * **<color #00a2e8>Days of incubation</color>**: 8 * **<color #00a2e8>Doublings</color>**: -0.2 * **<color #00a2e8>Numbers of reads</color>**: 14879101 ==== Screen Results ==== ^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^ |0/57|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/Bleomycin_5uM_Round-8_exp459.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="default" size="sm" modal="modal_go_sensitive">View</button>|<button type="default" size="sm" modal="modal_go_resistant">View</button>| <modal id='ScorePlot' size='lg' title='Bleomycin 5μM R08 exp459'> {{:chemogenomics:cranks_plots:exp459.png?nolink}} </modal> <modal id="modal_hits" size="sm" title="Top 30 S/R Genes"> ^Gene^CRANKS Score^FDR^ |[[:human_genes:S:SMG1|SMG1]]|-2.89|0.06| |[[:human_genes:Z:ZFYVE20|ZFYVE20]]|-2.79|0.13| |[[:human_genes:G:GPX4|GPX4]]|-2.71|0.06| |[[:human_genes:U:UBE4B|UBE4B]]|-2.65|0.06| |[[:human_genes:C:CHMP2A|CHMP2A]]|-2.61|0.26| |[[:human_genes:M:MUL1|MUL1]]|-2.52|0.13| |[[:human_genes:O:OSBP|OSBP]]|-2.50|0.13| |[[:human_genes:P:PSMD14|PSMD14]]|-2.46|0.54| |[[:human_genes:M:MTCH2|MTCH2]]|-2.45|0.24| |[[:human_genes:P:PRMT1|PRMT1]]|-2.34|0.34| |[[:human_genes:Z:ZNF880|ZNF880]]|-2.34|0.13| |[[:human_genes:Q:QSER1|QSER1]]|-2.33|0.13| |[[:human_genes:Z:ZBTB10|ZBTB10]]|-2.32|0.13| |[[:human_genes:M:MDM2|MDM2]]|-2.29|0.31| |[[:human_genes:D:DDX21|DDX21]]|-2.29|0.54| |[[:human_genes:E:EXOSC4|EXOSC4]]|-2.27|0.31| |[[:human_genes:H:HPS4|HPS4]]|-2.22|0.21| |[[:human_genes:D:DNM2|DNM2]]|-2.21|0.54| |[[:human_genes:N:NRL|NRL]]|-2.20|0.21| |[[:human_genes:A:ABRA|ABRA]]|-2.12|0.31| |[[:human_genes:T:TMEM202|TMEM202]]|-2.12|0.26| |[[:human_genes:C:CPSF2|CPSF2]]|-2.09|0.54| |[[:human_genes:T:TP53BP2|TP53BP2]]|-2.07|0.31| |[[:human_genes:R:RND1|RND1]]|-2.07|0.31| |[[:human_genes:P:PSMD1|PSMD1]]|-2.06|0.47| |[[:human_genes:T:TMEM174|TMEM174]]|-2.04|0.34| |[[:human_genes:A:ATXN1|ATXN1]]|-2.03|0.54| |[[:human_genes:B:BRIX1|BRIX1]]|-2.02|0.35| |[[:human_genes:P:PSMD6|PSMD6]]|-2.02|0.54| |[[:human_genes:R:RBM7|RBM7]]|-2.02|0.51| |[[:human_genes:M:METAP2|METAP2]]|2.61|0.03| |[[:human_genes:S:SLC4A7|SLC4A7]]|2.62|0.01| |[[:human_genes:F:FBXO11|FBXO11]]|2.62|<0.01| |[[:human_genes:H:HSPD1|HSPD1]]|2.66|<0.01| |[[:human_genes:M:MARCH5|MARCH5]]|2.74|<0.01| |[[:human_genes:A:ATP5A1|ATP5A1]]|2.74|0.02| |[[:human_genes:K:KCTD5|KCTD5]]|2.76|<0.01| |[[:human_genes:R:RABIF|RABIF]]|2.77|<0.01| |[[:human_genes:M:METAP1|METAP1]]|2.83|<0.01| |[[:human_genes:V:VDAC2|VDAC2]]|2.83|<0.01| |[[:human_genes:T:TRIAP1|TRIAP1]]|2.85|0.01| |[[:human_genes:T:THG1L|THG1L]]|2.86|<0.01| |[[:human_genes:R:RHOA|RHOA]]|2.88|<0.01| |[[:human_genes:T:TP53|TP53]]|2.92|<0.01| |[[:human_genes:T:TLE4|TLE4]]|3.04|<0.01| |[[:human_genes:D:DOHH|DOHH]]|3.15|<0.01| |[[:human_genes:S:SPOP|SPOP]]|3.21|0.00| |[[:human_genes:E:EXOC2|EXOC2]]|3.24|0.00| |[[:human_genes:R:RPTOR|RPTOR]]|3.41|0.00| |[[:human_genes:R:RIC8A|RIC8A]]|3.44|0.00| |[[:human_genes:E:ENY2|ENY2]]|3.62|0.00| |[[:human_genes:M:MED16|MED16]]|3.65|0.00| |[[:human_genes:G:GMPPB|GMPPB]]|3.67|0.01| |[[:human_genes:F:FAF2|FAF2]]|3.81|0.00| |[[:human_genes:U:UBQLN1|UBQLN1]]|4.09|0.00| |[[:human_genes:G:GNA13|GNA13]]|4.38|0.00| |[[:human_genes:P:PLAA|PLAA]]|4.40|0.00| |[[:human_genes:A:ATP2B1|ATP2B1]]|4.75|0.00| |[[:human_genes:B:BAK1|BAK1]]|6.61|0.00| |[[:human_genes:G:GJC1|GJC1]]|7.08|0.00| </modal> <modal id="modal_screen_similarity" size="lg" title="Correlated Screens"> ^Screen^Correlation^Plot^ |[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.152|<button type="primary" size="small" modal="1">View</button>| |[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.15|<button type="primary" size="small" modal="2">View</button>| |[[:results:exp199|Etoposide 0.3μM R05 exp199]]|0.15|<button type="primary" size="small" modal="3">View</button>| |[[:results:exp531|THZ1 0.06μM R08 exp531]]|0.142|<button type="primary" size="small" modal="4">View</button>| |[[:results:exp443|SNS-032 15μM R08 exp443]]|0.127|<button type="primary" size="small" modal="5">View</button>| |[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|0.121|<button type="primary" size="small" modal="6">View</button>| |[[:results:exp135|MS023 7μM R03 exp135]]|0.119|<button type="primary" size="small" modal="7">View</button>| |[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.119|<button type="primary" size="small" modal="8">View</button>| |[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.115|<button type="primary" size="small" modal="9">View</button>| |[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.105|<button type="primary" size="small" modal="10">View</button>| |[[:results:exp19|Etoposide 1μM R00 exp19]]|0.1|<button type="primary" size="small" modal="11">View</button>| |[[:results:exp34|Rotenone 20μM R00 exp34]]|0.099|<button type="primary" size="small" modal="12">View</button>| |[[:results:exp527|Tanespimycin 14μM R08 exp527]]|0.096|<button type="primary" size="small" modal="13">View</button>| |[[:results:exp515|PU-H71 1μM R08 exp515]]|0.095|<button type="primary" size="small" modal="14">View</button>| |[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.092|<button type="primary" size="small" modal="15">View</button>| |[[:results:exp512|Olaparib 4μM R08 exp512]]|0.09|<button type="primary" size="small" modal="16">View</button>| |[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|0.087|<button type="primary" size="small" modal="17">View</button>| |[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.083|<button type="primary" size="small" modal="18">View</button>| |[[:results:exp106|UM131593 0.2μM R03 exp106]]|0.08|<button type="primary" size="small" modal="19">View</button>| |[[:results:exp85|UM0129480 7μM R02 exp85]]|0.075|<button type="primary" size="small" modal="20">View</button>| |[[:results:exp474|CR131-b 0.005μM R08 exp474]]|0.074|<button type="primary" size="small" modal="21">View</button>| |[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.071|<button type="primary" size="small" modal="22">View</button>| |[[:results:exp134|MS023 2μM R03 exp134]]|0.071|<button type="primary" size="small" modal="23">View</button>| |[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.07|<button type="primary" size="small" modal="24">View</button>| |[[:results:exp22|MLN-4924 2μM R00 exp22]]|0.068|<button type="primary" size="small" modal="25">View</button>| |[[:results:exp485|GSK626616 14μM R08 exp485]]|0.064|<button type="primary" size="small" modal="26">View</button>| |[[:results:exp355|Dinaciclib 0.007μM R07 exp355]]|0.063|<button type="primary" size="small" modal="27">View</button>| |[[:results:exp468|CB-5083 0.4μM R08 exp468]]|0.061|<button type="primary" size="small" modal="28">View</button>| |[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|0.061|<button type="primary" size="small" modal="29">View</button>| |[[:results:exp502|Milciclib 2μM R08 exp502]]|0.057|<button type="primary" size="small" modal="30">View</button>| |[[:results:exp108|Vinblastine 0.2μM R03 exp108]]|0.055|<button type="primary" size="small" modal="31">View</button>| |[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|0.052|<button type="primary" size="small" modal="32">View</button>| |[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.166|<button type="primary" size="small" modal="33">View</button>| |[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|0.119|<button type="primary" size="small" modal="34">View</button>| |[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|0.115|<button type="primary" size="small" modal="35">View</button>| |[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.11|<button type="primary" size="small" modal="36">View</button>| |[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|0.109|<button type="primary" size="small" modal="37">View</button>| |[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.1|<button type="primary" size="small" modal="38">View</button>| |[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|0.085|<button type="primary" size="small" modal="39">View</button>| |[[:results:exp211|AICAR 240μM R05 exp211]]|0.079|<button type="primary" size="small" modal="40">View</button>| |[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.079|<button type="primary" size="small" modal="41">View</button>| |[[:results:exp539|42°C R08 exp539]]|0.067|<button type="primary" size="small" modal="42">View</button>| |[[:results:exp98|BI-6727 0.04μM R03 exp98]]|0.065|<button type="primary" size="small" modal="43">View</button>| |[[:results:exp96|BI-2536 0.02μM R03 exp96]]|0.063|<button type="primary" size="small" modal="44">View</button>| |[[:results:exp116|AICAR 240μM R03 exp116]]|0.055|<button type="primary" size="small" modal="45">View</button>| </modal> <modal id="1" size="lg" title="Bleomycin 5μM R08 exp459 vs Doxorubicin 0.02μM R08 exp478"> {{:chemogenomics:comparison_plots:exp459_vs_exp478.png?nolink |}} </modal> <modal id="2" size="lg" title="Bleomycin 5μM R08 exp459 vs Mitomycin-C 0.06μM R08 exp503"> {{:chemogenomics:comparison_plots:exp459_vs_exp503.png?nolink |}} </modal> <modal id="3" size="lg" title="Bleomycin 5μM R08 exp459 vs Etoposide 0.3μM R05 exp199"> {{:chemogenomics:comparison_plots:exp199_vs_exp459.png?nolink |}} </modal> <modal id="4" size="lg" title="Bleomycin 5μM R08 exp459 vs THZ1 0.06μM R08 exp531"> {{:chemogenomics:comparison_plots:exp459_vs_exp531.png?nolink |}} </modal> <modal id="5" size="lg" title="Bleomycin 5μM R08 exp459 vs SNS-032 15μM R08 exp443"> {{:chemogenomics:comparison_plots:exp443_vs_exp459.png?nolink |}} </modal> <modal id="6" size="lg" title="Bleomycin 5μM R08 exp459 vs Pimelic-diphenylamide-106 5μM R00 exp28"> {{:chemogenomics:comparison_plots:exp28_vs_exp459.png?nolink |}} </modal> <modal id="7" size="lg" title="Bleomycin 5μM R08 exp459 vs MS023 7μM R03 exp135"> {{:chemogenomics:comparison_plots:exp135_vs_exp459.png?nolink |}} </modal> <modal id="8" size="lg" title="Bleomycin 5μM R08 exp459 vs CI-1040 9.5μM R08 exp472"> {{:chemogenomics:comparison_plots:exp459_vs_exp472.png?nolink |}} </modal> <modal id="9" size="lg" title="Bleomycin 5μM R08 exp459 vs Staurosporine 0.02μM R08 exp524"> {{:chemogenomics:comparison_plots:exp459_vs_exp524.png?nolink |}} </modal> <modal id="10" size="lg" title="Bleomycin 5μM R08 exp459 vs RO-3307 4.7μM R02 exp80"> {{:chemogenomics:comparison_plots:exp459_vs_exp80.png?nolink |}} </modal> <modal id="11" size="lg" title="Bleomycin 5μM R08 exp459 vs Etoposide 1μM R00 exp19"> {{:chemogenomics:comparison_plots:exp19_vs_exp459.png?nolink |}} </modal> <modal id="12" size="lg" title="Bleomycin 5μM R08 exp459 vs Rotenone 20μM R00 exp34"> {{:chemogenomics:comparison_plots:exp34_vs_exp459.png?nolink |}} </modal> <modal id="13" size="lg" title="Bleomycin 5μM R08 exp459 vs Tanespimycin 14μM R08 exp527"> {{:chemogenomics:comparison_plots:exp459_vs_exp527.png?nolink |}} </modal> <modal id="14" size="lg" title="Bleomycin 5μM R08 exp459 vs PU-H71 1μM R08 exp515"> {{:chemogenomics:comparison_plots:exp459_vs_exp515.png?nolink |}} </modal> <modal id="15" size="lg" title="Bleomycin 5μM R08 exp459 vs Hippuristanol 0.12μM R08 exp489 no dilution day6"> {{:chemogenomics:comparison_plots:exp459_vs_exp489.png?nolink |}} </modal> <modal id="16" size="lg" title="Bleomycin 5μM R08 exp459 vs Olaparib 4μM R08 exp512"> {{:chemogenomics:comparison_plots:exp459_vs_exp512.png?nolink |}} </modal> <modal id="17" size="lg" title="Bleomycin 5μM R08 exp459 vs GSK461364A 0.1μM R03 exp126"> {{:chemogenomics:comparison_plots:exp126_vs_exp459.png?nolink |}} </modal> <modal id="18" size="lg" title="Bleomycin 5μM R08 exp459 vs Hippuristanol 0.12μM R08 exp488"> {{:chemogenomics:comparison_plots:exp459_vs_exp488.png?nolink |}} </modal> <modal id="19" size="lg" title="Bleomycin 5μM R08 exp459 vs UM131593 0.2μM R03 exp106"> {{:chemogenomics:comparison_plots:exp106_vs_exp459.png?nolink |}} </modal> <modal id="20" size="lg" title="Bleomycin 5μM R08 exp459 vs UM0129480 7μM R02 exp85"> {{:chemogenomics:comparison_plots:exp459_vs_exp85.png?nolink |}} </modal> <modal id="21" size="lg" title="Bleomycin 5μM R08 exp459 vs CR131-b 0.005μM R08 exp474"> {{:chemogenomics:comparison_plots:exp459_vs_exp474.png?nolink |}} </modal> <modal id="22" size="lg" title="Bleomycin 5μM R08 exp459 vs JQ1 0.8μM R08 exp435"> {{:chemogenomics:comparison_plots:exp435_vs_exp459.png?nolink |}} </modal> <modal id="23" size="lg" title="Bleomycin 5μM R08 exp459 vs MS023 2μM R03 exp134"> {{:chemogenomics:comparison_plots:exp134_vs_exp459.png?nolink |}} </modal> <modal id="24" size="lg" title="Bleomycin 5μM R08 exp459 vs Dorsomorphin 5μM R07 exp357"> {{:chemogenomics:comparison_plots:exp357_vs_exp459.png?nolink |}} </modal> <modal id="25" size="lg" title="Bleomycin 5μM R08 exp459 vs MLN-4924 2μM R00 exp22"> {{:chemogenomics:comparison_plots:exp22_vs_exp459.png?nolink |}} </modal> <modal id="26" size="lg" title="Bleomycin 5μM R08 exp459 vs GSK626616 14μM R08 exp485"> {{:chemogenomics:comparison_plots:exp459_vs_exp485.png?nolink |}} </modal> <modal id="27" size="lg" title="Bleomycin 5μM R08 exp459 vs Dinaciclib 0.007μM R07 exp355"> {{:chemogenomics:comparison_plots:exp355_vs_exp459.png?nolink |}} </modal> <modal id="28" size="lg" title="Bleomycin 5μM R08 exp459 vs CB-5083 0.4μM R08 exp468"> {{:chemogenomics:comparison_plots:exp459_vs_exp468.png?nolink |}} </modal> <modal id="29" size="lg" title="Bleomycin 5μM R08 exp459 vs Thimerosal 0.85μM R08 exp529"> {{:chemogenomics:comparison_plots:exp459_vs_exp529.png?nolink |}} </modal> <modal id="30" size="lg" title="Bleomycin 5μM R08 exp459 vs Milciclib 2μM R08 exp502"> {{:chemogenomics:comparison_plots:exp459_vs_exp502.png?nolink |}} </modal> <modal id="31" size="lg" title="Bleomycin 5μM R08 exp459 vs Vinblastine 0.2μM R03 exp108"> {{:chemogenomics:comparison_plots:exp108_vs_exp459.png?nolink |}} </modal> <modal id="32" size="lg" title="Bleomycin 5μM R08 exp459 vs LY2090314 0.003μM R08 exp500 no dilution day6"> {{:chemogenomics:comparison_plots:exp459_vs_exp500.png?nolink |}} </modal> <modal id="33" size="lg" title="Benzoate 20000μM R08 exp456 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp456_vs_exp459.png?nolink |}} </modal> <modal id="34" size="lg" title="Actinomycin-D 0.001μM R00 exp3 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp3_vs_exp459.png?nolink |}} </modal> <modal id="35" size="lg" title="5-Fluorouracil 20μM R00 exp2 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp2_vs_exp459.png?nolink |}} </modal> <modal id="36" size="lg" title="Atovaquone 15μM R08 exp451 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp451_vs_exp459.png?nolink |}} </modal> <modal id="37" size="lg" title="6-Thio-2-deoxyguanosine 2μM R06 exp259 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp259_vs_exp459.png?nolink |}} </modal> <modal id="38" size="lg" title="Aphidicolin 0.4μM R08 exp440 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp440_vs_exp459.png?nolink |}} </modal> <modal id="39" size="lg" title="Ammonium tetrathiomolybdate 10μM R08 exp448 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp448_vs_exp459.png?nolink |}} </modal> <modal id="40" size="lg" title="AICAR 240μM R05 exp211 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp211_vs_exp459.png?nolink |}} </modal> <modal id="41" size="lg" title="Artemisinin 50μM R08 exp450 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp450_vs_exp459.png?nolink |}} </modal> <modal id="42" size="lg" title="42°C R08 exp539 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp459_vs_exp539.png?nolink |}} </modal> <modal id="43" size="lg" title="BI-6727 0.04μM R03 exp98 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp459_vs_exp98.png?nolink |}} </modal> <modal id="44" size="lg" title="BI-2536 0.02μM R03 exp96 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp459_vs_exp96.png?nolink |}} </modal> <modal id="45" size="lg" title="AICAR 240μM R03 exp116 vs Bleomycin 5μM R08 exp459"> {{:chemogenomics:comparison_plots:exp116_vs_exp459.png?nolink |}} </modal> <modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">No GO term hits below threshold. (FDR <0.05)</modal> <modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">No GO term hits below threshold. (FDR <0.05)</modal> Last modified: 2026/01/15 21:36by 127.0.0.1