BAGE4 [The Human Chemical-Genetic Interaction Map Project]

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======= BAGE4 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: BAGE4
  * **<color #00a2e8>Official Name</color>**: BAGE family member 4
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=85317|85317]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q86Y28|Q86Y28]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=BAGE4&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20BAGE4|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Unknown. Candidate gene encoding tumor antigens.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|BAGE|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|extracellular region|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp17|DABN 20μM R00 exp17]]|-2.48|
|[[:results:exp360|Genistein 15μM R07 exp360]]|-1.9|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|-1.71|
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|1.74|
|[[:results:exp418|Tunicamycin 0.04μM R07 exp418]]|1.74|
|[[:results:exp389|PF-06409577 20μM R07 exp389]]|1.78|
|[[:results:exp72|LB-100 4.1μM R02 exp72]]|1.84|
|[[:results:exp365|I-BRD9 4μM R07 exp365]]|1.88|
|[[:results:exp340|BN82002 4μM R07 exp340]]|1.89|
|[[:results:exp380|NMS-873 0.07μM R07 exp380]]|1.91|
|[[:results:exp73|LJH685 5μM R02 exp73]]|1.95|
|[[:results:exp463|Caffeine 2600μM R08 exp463]]|2|
|[[:results:exp355|Dinaciclib 0.007μM R07 exp355]]|2.2|
|[[:results:exp281|Disulfiram 4.3μM R06 exp281]]|2.3|
|[[:results:exp77|Prochlorperazine 5.2μM R02 exp77]]|2.55|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:cep192|CEP192]]|0.449|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.437|
|[[:human genes:k:kctd17|KCTD17]]|0.435|
|[[:human genes:c:chd4|CHD4]]|0.432|
|[[:human genes:o:oxer1|OXER1]]|0.428|
|[[:human genes:l:lad1|LAD1]]|0.423|
|[[:human genes:p:psma6|PSMA6]]|0.421|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.421|
|[[:human genes:n:nol6|NOL6]]|0.414|
|[[:human genes:p:pole|POLE]]|0.413|
|[[:human genes:s:s1pr4|S1PR4]]|0.412|
|[[:human genes:r:rps7|RPS7]]|0.412|
|[[:human genes:i:ints5|INTS5]]|0.408|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.407|
|[[:human genes:t:ticrr|TICRR]]|0.403|
|[[:human genes:d:ddx21|DDX21]]|0.403|
|[[:human genes:r:rps2|RPS2]]|0.402|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.401|
|[[:human genes:p:psmc6|PSMC6]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1478
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: N/A 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='BAGE4 Expression in NALM6 Cells: N/A'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>