C4orf29 [The Human Chemical-Genetic Interaction Map Project]

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======= C4orf29 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ABHD18
  * **<color #00a2e8>Official Name</color>**: abhydrolase domain containing 18
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=80167|80167]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q0P651|Q0P651]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=C4orf29&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C4orf29|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Abhydrolase 6|
|DUF2048|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|extracellular region|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp445|∆-9-Tetrahydrocannabinol 30μM R08 exp445]]|-2.46|
|[[:results:exp18|Doxycycline 10μM R00 exp18]]|-2.22|
|[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|-1.95|
|[[:results:exp358|FK-506 5μM R07 exp358]]|-1.77|
|[[:results:exp538|ZLN024 50μM R08 exp538]]|-1.72|
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|1.72|
|[[:results:exp182|IU1-47 25μM R04 exp182]]|1.75|
|[[:results:exp77|Prochlorperazine 5.2μM R02 exp77]]|1.76|
|[[:results:exp79|Q15 2.7μM R02 exp79]]|1.88|
|[[:results:exp508|NN-Dimethylsphingosine 2.5μM R08 exp508]]|2.29|
|[[:results:exp191|Hypoxia 5%O2 R04 exp191]]|2.32|
|[[:results:exp103|Taxol 0.004μM R03 exp103]]|2.79|
|[[:results:exp274|Citral 50μM R06 exp274]]|2.92|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:clpb|CLPB]]|0.413|
|[[:human genes:s:slc25a20|SLC25A20]]|0.406|
|[[:human genes:t:timm8a|TIMM8A]]|0.403|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2291
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.81 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='C4ORF29 Expression in NALM6 Cells: 5.81'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>