CXorf67 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= CXorf67 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: EZHIP
  * **<color #00a2e8>Official Name</color>**: EZH inhibitory protein
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=340602|340602]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q86X51|Q86X51]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CXorf67&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CXorf67|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/301036|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|negative regulation of histone H3-K27 methylation|
|regulation of histone H3-K27 methylation|
|negative regulation of histone methylation|
|negative regulation of histone modification|
|negative regulation of chromatin organization|
|regulation of histone methylation|
|negative regulation of chromosome organization|
|regulation of histone modification|
|regulation of chromatin organization|
|regulation of chromosome organization|
|negative regulation of organelle organization|
|negative regulation of protein modification process|
|negative regulation of cellular component organization|
|negative regulation of cellular protein metabolic process|
|negative regulation of protein metabolic process|
|regulation of organelle organization|
|regulation of protein modification process|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp53|Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53]]|-2.92|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|-2.7|
|[[:results:exp49|NFN1 0.1μM R01 exp49]]|-2.42|
|[[:results:exp33|Rotenone 2μM R00 exp33]]|-2.08|
|[[:results:exp52|Ribavirin 10μM R01 exp52]]|-2.07|
|[[:results:exp151|SGC0946 7μM R03 exp151]]|-2.07|
|[[:results:exp97|BI-6727 0.0125μM R03 exp97]]|-2|
|[[:results:exp153|SGC2096 2.6μM R03 exp153]]|-1.81|
|[[:results:exp507|Monensin 0.3μM R08 exp507]]|-1.75|
|[[:results:exp45|Docetaxel 0.002μM R01 exp45]]|-1.74|
|[[:results:exp134|MS023 2μM R03 exp134]]|-1.73|
|[[:results:exp243|S-trityl-L-cysteine 0.5μM R05 exp243]]|-1.7|
|[[:results:exp341|BRD2 inhibitor II 20μM R07 exp341]]|1.7|
|[[:results:exp279|D-Fructose 10000μM R06 exp279]]|1.74|
|[[:results:exp300|VE-822 0.04μM R06 exp300]]|1.85|
|[[:results:exp303|39°C R06 exp303]]|1.93|
|[[:results:exp90|WYE-354 6μM R02 exp90]]|2.21|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 6485
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -7.68 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CXORF67 Expression in NALM6 Cells: -7.68'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>