FAM72C [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= FAM72C =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: FAM72C
  * **<color #00a2e8>Official Name</color>**: family with sequence similarity 72 member C
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=554282|554282]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/H0Y354|H0Y354]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=FAM72C&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20FAM72C|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/616853|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|intracellular membrane-bounded organelle|
|membrane|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp199|Etoposide 0.3μM R05 exp199]]|-2.11|
|[[:results:exp330|5-Azacytidine 2μM R07 exp330]]|-1.82|
|[[:results:exp471|Cholesterol 0.003 to 0.006 to 0.1μM on day2 then day6 R08 exp471]]|-1.8|
|[[:results:exp486|Heregulin-B 44ng/ml R08 exp486]]|-1.76|
|[[:results:exp493|IL-3 9ng/ml R08 exp493]]|-1.74|
|[[:results:exp507|Monensin 0.3μM R08 exp507]]|-1.74|
|[[:results:exp164|Q15 1 to 2μM on day4 R04 exp164]]|-1.74|
|[[:results:exp183|IU1-C 25μM R04 exp183]]|1.72|
|[[:results:exp141|Nifurtimox 1μM R03 exp141]]|1.74|
|[[:results:exp246|UM0011500 10μM R05 exp246]]|1.75|
|[[:results:exp288|HMS-I2 10μM R06 exp288]]|1.79|
|[[:results:exp107|UMK57 0.6μM R03 exp107]]|1.79|
|[[:results:exp97|BI-6727 0.0125μM R03 exp97]]|1.8|
|[[:results:exp301|VER-155008 3.9μM R06 exp301]]|1.84|
|[[:results:exp187|proTAME 5μM R04 exp187]]|1.85|
|[[:results:exp23|Nocodazole 0.02μM R00 exp23]]|1.86|
|[[:results:exp146|Quinacrine 2.5μM R03 exp146]]|2.12|
|[[:results:exp262|Alda-1 10μM R06 exp262]]|2.14|
|[[:results:exp8|Brefeldin A 0.02μM R00 exp8]]|2.3|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|2.32|
|[[:results:exp270|Campthothecin 0.001μM R06 exp270]]|2.5|
|[[:results:exp132|Metformin 40μM R03 exp132]]|3.21|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 7375
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.89 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='FAM72C Expression in NALM6 Cells: 4.89'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>