GOLGA6L4 [The Human Chemical-Genetic Interaction Map Project]

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======= GOLGA6L4 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA6L4
  * **<color #00a2e8>Official Name</color>**: golgin A6 family like 4
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=643707|643707]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A6NEF3|A6NEF3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA6L4&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA6L4|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi apparatus|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|-1.71|
|[[:results:exp182|IU1-47 25μM R04 exp182]]|1.75|
|[[:results:exp165|RO-3306 3 to 4μM on day4 R04 exp165]]|1.78|
|[[:results:exp53|Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53]]|1.95|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:psmb2|PSMB2]]|0.544|
|[[:human genes:t:tceb3c|TCEB3C]]|0.538|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.531|
|[[:human genes:c:cbwd5|CBWD5]]|0.523|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.52|
|[[:human genes:c:cbwd3|CBWD3]]|0.518|
|[[:human genes:p:psmb4|PSMB4]]|0.516|
|[[:human genes:b:bysl|BYSL]]|0.514|
|[[:human genes:c:cbwd6|CBWD6]]|0.5|
|[[:human genes:w:wdr87|WDR87]]|0.488|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.474|
|[[:human genes:r:rrp7a|RRP7A]]|0.473|
|[[:human genes:p:polr2j3|POLR2J3]]|0.471|
|[[:human genes:p:pola1|POLA1]]|0.467|
|[[:human genes:p:pwp2|PWP2]]|0.462|
|[[:human genes:c:chd4|CHD4]]|0.461|
|[[:human genes:t:ticrr|TICRR]]|0.457|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.455|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.454|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.454|
|[[:human genes:r:rps5|RPS5]]|0.451|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.451|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.45|
|[[:human genes:r:rpl9|RPL9]]|0.449|
|[[:human genes:r:rps19|RPS19]]|0.445|
|[[:human genes:p:psmd3|PSMD3]]|0.445|
|[[:human genes:p:psma6|PSMA6]]|0.443|
|[[:human genes:c:c14orf93|C14orf93]]|0.443|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.44|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.44|
|[[:human genes:m:myo18a|MYO18A]]|0.439|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.439|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.439|
|[[:human genes:s:slc4a1|SLC4A1]]|0.439|
|[[:human genes:f:fam160a1|FAM160A1]]|0.438|
|[[:human genes:k:kctd17|KCTD17]]|0.438|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.436|
|[[:human genes:r:rpl35|RPL35]]|0.436|
|[[:human genes:m:mt1e|MT1E]]|0.436|
|[[:human genes:t:twistnb|TWISTNB]]|0.435|
|[[:human genes:c:copa|COPA]]|0.434|
|[[:human genes:a:aatf|AATF]]|0.433|
|[[:human genes:c:cdh24|CDH24]]|0.433|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.432|
|[[:human genes:p:psmb1|PSMB1]]|0.43|
|[[:human genes:s:supt5h|SUPT5H]]|0.429|
|[[:human genes:p:psmc5|PSMC5]]|0.428|
|[[:human genes:z:znf830|ZNF830]]|0.428|
|[[:human genes:c:cox7a2l|COX7A2L]]|0.426|
|[[:human genes:s:sart1|SART1]]|0.425|
|[[:human genes:n:nupl1|NUPL1]]|0.425|
|[[:human genes:h:hinfp|HINFP]]|0.425|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.423|
|[[:human genes:a:akirin2|AKIRIN2]]|0.422|
|[[:human genes:f:fbxw9|FBXW9]]|0.422|
|[[:human genes:u:utp20|UTP20]]|0.422|
|[[:human genes:r:rps2|RPS2]]|0.42|
|[[:human genes:d:dimt1|DIMT1]]|0.42|
|[[:human genes:c:cdc6|CDC6]]|0.419|
|[[:human genes:c:chaf1a|CHAF1A]]|0.419|
|[[:human genes:r:rpl6|RPL6]]|0.419|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.419|
|[[:human genes:c:copg1|COPG1]]|0.419|
|[[:human genes:o:orc1|ORC1]]|0.419|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.418|
|[[:human genes:n:npipb5|NPIPB5]]|0.418|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.417|
|[[:human genes:a:apc2|APC2]]|0.417|
|[[:human genes:d:disp2|DISP2]]|0.416|
|[[:human genes:r:rbbp5|RBBP5]]|0.415|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.415|
|[[:human genes:d:dtl|DTL]]|0.414|
|[[:human genes:t:tfip11|TFIP11]]|0.413|
|[[:human genes:p:polr2f|POLR2F]]|0.412|
|[[:human genes:v:vps28|VPS28]]|0.412|
|[[:human genes:p:pole|POLE]]|0.412|
|[[:human genes:a:acsf2|ACSF2]]|0.411|
|[[:human genes:n:nup160|NUP160]]|0.41|
|[[:human genes:a:ankle1|ANKLE1]]|0.41|
|[[:human genes:c:col2a1|COL2A1]]|0.409|
|[[:human genes:r:rilpl1|RILPL1]]|0.409|
|[[:human genes:c:cacna1a|CACNA1A]]|0.407|
|[[:human genes:s:slc38a7|SLC38A7]]|0.407|
|[[:human genes:p:pld3|PLD3]]|0.407|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.406|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.405|
|[[:human genes:s:snrpa1|SNRPA1]]|0.404|
|[[:human genes:a:aqr|AQR]]|0.404|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.404|
|[[:human genes:t:tyms|TYMS]]|0.403|
|[[:human genes:g:golga8o|GOLGA8O]]|0.403|
|[[:human genes:x:xylt2|XYLT2]]|0.403|
|[[:human genes:a:atp13a1|ATP13A1]]|0.402|
|[[:human genes:k:krt2|KRT2]]|0.402|
|[[:human genes:o:orc6|ORC6]]|0.402|
|[[:human genes:p:parp3|PARP3]]|0.401|
|[[:human genes:n:nbpf16|NBPF16]]|0.401|
|[[:human genes:p:plk1|PLK1]]|0.401|
|[[:human genes:s:ssh2|SSH2]]|0.4|
|[[:human genes:r:rps20|RPS20]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1696
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.34 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA6L4 Expression in NALM6 Cells: 4.34'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>