GOLGA8H [The Human Chemical-Genetic Interaction Map Project]

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======= GOLGA8H =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA8H
  * **<color #00a2e8>Official Name</color>**: golgin A8 family member H
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=728498|728498]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P0CJ92|P0CJ92]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA8H&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA8H|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi cis cisterna|
|cis-Golgi network|
|Golgi cisterna membrane|
|spindle assembly|
|Golgi organization|
|spindle organization|
|endomembrane system organization|
|microtubule cytoskeleton organization|
|microtubule-based process|
|organelle assembly|
|Golgi apparatus|
|cell cycle process|
|cytoskeleton organization|
|cell cycle|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp469|CFI-400945 25μM R08 exp469]]|-3.43|
|[[:results:exp64|Nocodazole 0.2μM R02 exp64]]|-2.45|
|[[:results:exp134|MS023 2μM R03 exp134]]|-2.24|
|[[:results:exp447|Amiloride 100μM R08 exp447]]|-2.16|
|[[:results:exp519|RS-1 10μM R08 exp519]]|-2.14|
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|-2.14|
|[[:results:exp534|Trientine 500μM R08 exp534]]|-2.13|
|[[:results:exp98|BI-6727 0.04μM R03 exp98]]|-2.1|
|[[:results:exp539|42°C R08 exp539]]|-2.09|
|[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|-2.03|
|[[:results:exp93|DABN racemic mixture R03 exp93]]|-1.97|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|-1.96|
|[[:results:exp121|Golgicide-A 2μM R03 exp121]]|-1.94|
|[[:results:exp107|UMK57 0.6μM R03 exp107]]|-1.94|
|[[:results:exp335|Aminopterin 0.005μM R07 exp335]]|-1.88|
|[[:results:exp513|ONC212 0.15μM R08 exp513]]|-1.82|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|-1.78|
|[[:results:exp128|GSK591 2.6μM R03 exp128]]|-1.78|
|[[:results:exp350|Deferoxamine 11μM R07 exp350]]|-1.77|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|-1.74|
|[[:results:exp136|MS094 2μM R03 exp136]]|1.7|
|[[:results:exp303|39°C R06 exp303]]|1.74|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|1.78|
|[[:results:exp38|Wortmannin 5μM R00 exp38]]|1.83|
|[[:results:exp418|Tunicamycin 0.04μM R07 exp418]]|1.86|
|[[:results:exp212|Phenformin 20μM R05 exp212]]|1.88|
|[[:results:exp16|DABN 2μM R00 exp16]]|1.9|
|[[:results:exp379|MSC2530818 10μM R07 exp379]]|1.99|
|[[:results:exp52|Ribavirin 10μM R01 exp52]]|1.99|
|[[:results:exp247|UM0130462 0.025 to 0.035μM day4 R05 exp247]]|2|
|[[:results:exp6|Bortezomib 0.005μM R00 exp6]]|2.06|
|[[:results:exp261|ABT-702 5μM R06 exp261]]|2.12|
|[[:results:exp239|PFI-2 4μM R05 exp239]]|2.21|
|[[:results:exp41|BI-2536 0.001μM R01 exp41]]|2.27|
|[[:results:exp467|CAY10603 0.55μM R08 exp467]]|2.31|
|[[:results:exp101|Nicotinamide 1000μM R03 exp101]]|2.37|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|2.44|
|[[:results:exp42|BI-6727 0.001μM R01 exp42]]|2.82|
|[[:results:exp354|Diepoxybutane 3μM R07 exp354]]|2.9|
|[[:results:exp291|LLY-284 2.6μM R06 exp291]]|3.38|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|3.55|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.468|
|[[:human genes:r:rbm39|RBM39]]|0.451|
|[[:human genes:t:tfip11|TFIP11]]|0.44|
|[[:human genes:s:supt5h|SUPT5H]]|0.431|
|[[:human genes:a:ahctf1|AHCTF1]]|0.429|
|[[:human genes:s:snrpa1|SNRPA1]]|0.428|
|[[:human genes:c:cdc73|CDC73]]|0.427|
|[[:human genes:s:syt9|SYT9]]|0.423|
|[[:human genes:p:plk4|PLK4]]|0.422|
|[[:human genes:p:psmd3|PSMD3]]|0.416|
|[[:human genes:p:psmd2|PSMD2]]|0.412|
|[[:human genes:l:lrr1|LRR1]]|0.405|
|[[:human genes:c:cdc6|CDC6]]|0.402|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1231
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -0.93 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA8H Expression in NALM6 Cells: -0.93'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>