MST1L [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= MST1L =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: N/A
  * **<color #00a2e8>Official Name</color>**: N/A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: N/A
  * **<color #00a2e8>UniProt</color>**: N/A
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=MST1L&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20MST1L|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Trypsin|
|Kringle|
|PAN 1|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|positive regulation of mammary gland epithelial cell proliferation|
|regulation of mammary gland epithelial cell proliferation|
|regulation of macrophage chemotaxis|
|regulation of macrophage migration|
|regulation of leukocyte chemotaxis|
|serine-type endopeptidase activity|
|positive regulation of epithelial cell proliferation|
|regulation of leukocyte migration|
|regulation of chemotaxis|
|regulation of epithelial cell proliferation|
|regulation of cell migration|
|regulation of cell motility|
|positive regulation of cell population proliferation|
|regulation of locomotion|
|regulation of cellular component movement|
|regulation of response to external stimulus|
|proteolysis|
|positive regulation of developmental process|
|regulation of cell population proliferation|
|regulation of immune system process|
|positive regulation of multicellular organismal process|
|extracellular region|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp425|Beta-Estradiol 0.55μM R07 exp425]]|-1.99|
|[[:results:exp99|NFN1 0.4μM R03 exp99]]|-1.88|
|[[:results:exp130|JQ1 0.01μM R03 exp130]]|-1.83|
|[[:results:exp392|PT-1 25μM R07 exp392]]|-1.81|
|[[:results:exp106|UM131593 0.2μM R03 exp106]]|-1.8|
|[[:results:exp508|NN-Dimethylsphingosine 2.5μM R08 exp508]]|-1.78|
|[[:results:exp360|Genistein 15μM R07 exp360]]|-1.76|
|[[:results:exp417|Tubastatin-A 2.5μM R07 exp417]]|-1.73|
|[[:results:exp462|Cadmium 60μM R08 exp462]]|2.28|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 16835
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: N/A 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NA Expression in NALM6 Cells: N/A'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>