NPIPA1 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= NPIPA1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NPIPA1
  * **<color #00a2e8>Official Name</color>**: nuclear pore complex interacting protein family member A1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=9284|9284]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q9UND3|Q9UND3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=NPIPA1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20NPIPA1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/606406|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|NPIP|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|nuclear pore|
|mRNA transport|
|RNA transport|
|nucleic acid transport|
|establishment of RNA localization|
|RNA localization|
|nuclear membrane|
|nucleobase-containing compound transport|
|protein transport|
|peptide transport|
|amide transport|
|establishment of protein localization|
|nitrogen compound transport|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 169/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|5/28|
|blood|15/28|
|bone|10/26|
|breast|5/33|
|central nervous system|6/56|
|cervix|2/4|
|colorectal|6/17|
|esophagus|3/13|
|fibroblast|0/1|
|gastric|4/16|
|kidney|2/21|
|liver|8/20|
|lung|19/75|
|lymphocyte|3/16|
|ovary|2/26|
|pancreas|2/24|
|peripheral nervous system|5/16|
|plasma cell|3/15|
|prostate|0/1|
|skin|4/24|
|soft tissue|0/9|
|thyroid|1/2|
|upper aerodigestive|5/22|
|urinary tract|7/29|
|uterus|2/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 941
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.95 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NPIPA1 Expression in NALM6 Cells: 6.95'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>