NPIPA3 [The Human Chemical-Genetic Interaction Map Project]

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======= NPIPA3 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NPIPA3
  * **<color #00a2e8>Official Name</color>**: nuclear pore complex interacting protein family member A3
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=642778|642778]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/F8WFD2|F8WFD2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=NPIPA3&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20NPIPA3|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|NPIP|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp317|Geldanamycin 0.015 to 0.05μM on day4 R07 exp317]]|-2.77|
|[[:results:exp25|Oligomycin-A 2μM R00 exp25]]|-2.1|
|[[:results:exp429|Rapamycin 0.001μM R08 exp429]]|-1.88|
|[[:results:exp32|Rifampicin 10μM R00 exp32]]|-1.78|
|[[:results:exp142|OICR-9429 10μM R03 exp142]]|1.7|
|[[:results:exp517|Quercetin 20μM R08 exp517]]|1.71|
|[[:results:exp462|Cadmium 60μM R08 exp462]]|1.82|
|[[:results:exp97|BI-6727 0.0125μM R03 exp97]]|1.92|
|[[:results:exp218|A-395 10μM R05 exp218]]|2.01|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 5877
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 3.96 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NPIPA3 Expression in NALM6 Cells: 3.96'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>