QSER1 [The Human Chemical-Genetic Interaction Map Project]

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======= QSER1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: QSER1
  * **<color #00a2e8>Official Name</color>**: glutamine and serine rich 1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=79832|79832]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q2KHR3|Q2KHR3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=QSER1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20QSER1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/619440|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp482|Fas-L 44ng/ml R08 exp482]]|-2.85|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|-2.33|
|[[:results:exp429|Rapamycin 0.001μM R08 exp429]]|-2.26|
|[[:results:exp365|I-BRD9 4μM R07 exp365]]|-2.14|
|[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|-2.14|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|-1.99|
|[[:results:exp229|Dimethyloxaloylglycine 100μM R05 exp229]]|-1.84|
|[[:results:exp162|BI-D1870 2μM R04 exp162]]|-1.83|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|-1.78|
|[[:results:exp223|Cabazitaxel 0.001μM R05 exp223]]|-1.75|
|[[:results:exp469|CFI-400945 25μM R08 exp469]]|-1.74|
|[[:results:exp72|LB-100 4.1μM R02 exp72]]|-1.72|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|-1.71|
|[[:results:exp346|CoCl2 18μM R07 exp346]]|1.7|
|[[:results:exp12|Chloramphenicol 2μM R00 exp12]]|1.74|
|[[:results:exp51|Nifuroxazide 1μM R01 exp51]]|1.81|
|[[:results:exp101|Nicotinamide 1000μM R03 exp101]]|1.87|
|[[:results:exp147|Resveratrol 16μM R03 exp147]]|1.92|
|[[:results:exp426|FBS-Wisent 0.1 R07 exp426]]|1.93|
|[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|2.15|
|[[:results:exp156|UNC2400 2μM R03 exp156]]|2.41|
|[[:results:exp108|Vinblastine 0.2μM R03 exp108]]|2.67|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 8938
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 7.01 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='QSER1 Expression in NALM6 Cells: 7.01'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>