RASSF10 [The Human Chemical-Genetic Interaction Map Project]

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======= RASSF10 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: RASSF10
  * **<color #00a2e8>Official Name</color>**: Ras association domain family member 10
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=644943|644943]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A6NK89|A6NK89]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=RASSF10&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20RASSF10|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/614713|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|positive regulation of neural precursor cell proliferation|
|regulation of neural precursor cell proliferation|
|spindle pole|
|microtubule organizing center|
|positive regulation of neurogenesis|
|positive regulation of nervous system development|
|positive regulation of cell development|
|regulation of neurogenesis|
|positive regulation of cell population proliferation|
|regulation of nervous system development|
|regulation of cell development|
|positive regulation of cell differentiation|
|positive regulation of developmental process|
|generation of neurons|
|regulation of cell population proliferation|
|neurogenesis|
|positive regulation of multicellular organismal process|
|regulation of cell differentiation|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp349|Cytochalasin-B 5μM R07 exp349]]|-1.92|
|[[:results:exp18|Doxycycline 10μM R00 exp18]]|1.92|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:r:rrm1|RRM1]]|0.468|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 6253
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 0.41 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='RASSF10 Expression in NALM6 Cells: 0.41'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>