RTCB [The Human Chemical-Genetic Interaction Map Project]

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======= RTCB =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: RTCB
  * **<color #00a2e8>Official Name</color>**: RNA 2',3'-cyclic phosphate and 5'-OH ligase
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=51493|51493]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q9Y3I0|Q9Y3I0]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=RTCB&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20RTCB|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/613901|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'- phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. {ECO:0000269|PubMed:21311021, ECO:0000269|PubMed:24870230}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|UPF0027|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|RNA ligase (ATP) activity|
|tRNA exon ligation|
|tRNA exon ligation utilizing 2,3 cyclic phosphate of 5-exon as source of linkage phosphate|
|RNA exon ligation|
|tRNA-splicing ligase complex|
|vinculin binding|
|tRNA splicing, via endonucleolytic cleavage and ligation|
|RNA splicing, via endonucleolytic cleavage and ligation|
|tRNA processing|
|placenta development|
|nuclear envelope|
|tRNA metabolic process|
|in utero embryonic development|
|ncRNA processing|
|RNA splicing|
|reproductive structure development|
|reproductive system development|
|ncRNA metabolic process|
|chordate embryonic development|
|embryo development ending in birth or egg hatching|
|developmental process involved in reproduction|
|intracellular membrane-bounded organelle|
|RNA processing|
|endoplasmic reticulum membrane|
|embryo development|
|RNA binding|
|reproductive process|
|reproduction|
|ATP binding|
|RNA metabolic process|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp375|Lenalidomide 20μM R07 exp375]]|-2.57|
|[[:results:exp421|VHL-ligand-1 20μM R07 exp421]]|-2.48|
|[[:results:exp514|Phorbol-12-myristate-13-acetate 0.57μM R08 exp514]]|-2.44|
|[[:results:exp341|BRD2 inhibitor II 20μM R07 exp341]]|-2.23|
|[[:results:exp185|L-BMAA 500 to 750μM on day4 R04 exp185]]|-2.19|
|[[:results:exp239|PFI-2 4μM R05 exp239]]|-2.12|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|-2.11|
|[[:results:exp419|Tunicamycin 0.04 to 0.075μM  on day4 R07 exp419]]|-2.11|
|[[:results:exp160|Ribavirin 10 to 15μM on day4 R04 exp160]]|-2.09|
|[[:results:exp333|All-trans-Retinoic-Acid 8μM R07 exp333]]|-2.07|
|[[:results:exp347|Cyclosporin-A 0.8μM R07 exp347]]|-2.07|
|[[:results:exp177|Apcin 25μM plus proTAME 2μM R04 exp177]]|-2.06|
|[[:results:exp247|UM0130462 0.025 to 0.035μM day4 R05 exp247]]|-2.04|
|[[:results:exp283|Glyphosate 1000μM R06 exp283]]|-2.02|
|[[:results:exp340|BN82002 4μM R07 exp340]]|-2.01|
|[[:results:exp490|Hydroxychloroquine 30μM R08 exp490]]|-1.99|
|[[:results:exp476|Dihydrosphingosine 8μM R08 exp476]]|-1.94|
|[[:results:exp14|Cycloheximide 0.02μM R00 exp14]]|-1.93|
|[[:results:exp528|TGF-beta1 44ng/ml R08 exp528]]|-1.93|
|[[:results:exp344|Chlorpromazine 10μM R07 exp344]]|-1.89|
|[[:results:exp184|Ixabepilone 0.004 to 0.005μM on day4 R04 exp184]]|-1.89|
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|-1.88|
|[[:results:exp516|Pyrazinamide 100μM R08 exp516]]|-1.87|
|[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|-1.86|
|[[:results:exp372|Ibrutinib 1μM R07 exp372]]|-1.86|
|[[:results:exp332|Adefovir 20μM R07 exp332]]|-1.85|
|[[:results:exp473|Cincreasin 100μM R08 exp473]]|-1.82|
|[[:results:exp520|Rucaparib 6.5μM R08 exp520]]|-1.81|
|[[:results:exp455|Benzoate 10000μM R08 exp455]]|-1.8|
|[[:results:exp418|Tunicamycin 0.04μM R07 exp418]]|-1.8|
|[[:results:exp346|CoCl2 18μM R07 exp346]]|-1.77|
|[[:results:exp405|Tenofovir 10μM R07 exp405]]|-1.77|
|[[:results:exp342|Calcium Ionophore 0.4μM R07 exp342]]|-1.76|
|[[:results:exp248|UM0131023 0.05μM R05 exp248]]|-1.76|
|[[:results:exp494|Isoniazid 100μM R08 exp494]]|-1.75|
|[[:results:exp389|PF-06409577 20μM R07 exp389]]|-1.75|
|[[:results:exp462|Cadmium 60μM R08 exp462]]|-1.74|
|[[:results:exp42|BI-6727 0.001μM R01 exp42]]|-1.72|
|[[:results:exp308|Rapamycin 2μM plus FK-506 5μM R07 exp308]]|-1.72|
|[[:results:exp306|Rapamycin 2μM R07 exp306]]|-1.72|
|[[:results:exp530|Thioridazine 5μM R08 exp530]]|-1.71|
|[[:results:exp336|Asunaprenir 3μM R07 exp336]]|-1.7|
|[[:results:exp12|Chloramphenicol 2μM R00 exp12]]|-1.7|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|1.7|
|[[:results:exp244|SB743921 0.001μM R05 exp244]]|1.7|
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|1.75|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|1.76|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|1.76|
|[[:results:exp401|SNS-032 25μM R07 exp401]]|1.86|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|1.93|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|1.96|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|2.09|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|2.11|
|[[:results:exp94|Nocodazole 0.1μM R03 exp94]]|2.14|
|[[:results:exp111|R-DABN 8μM R03 exp111]]|2.15|
|[[:results:exp93|DABN racemic mixture R03 exp93]]|2.21|
|[[:results:exp98|BI-6727 0.04μM R03 exp98]]|2.34|
|[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|2.5|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|2.5|
|[[:results:exp108|Vinblastine 0.2μM R03 exp108]]|2.56|
|[[:results:exp126|GSK461364A 0.1μM R03 exp126]]|2.58|
|[[:results:exp507|Monensin 0.3μM R08 exp507]]|2.6|
|[[:results:exp22|MLN-4924 2μM R00 exp22]]|3.24|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:thg1l|THG1L]]|0.718|
|[[:human genes:d:dpagt1|DPAGT1]]|0.704|
|[[:human genes:g:gfpt1|GFPT1]]|0.69|
|[[:human genes:u:uap1|UAP1]]|0.658|
|[[:human genes:r:rptor|RPTOR]]|0.648|
|[[:human genes:g:gmppb|GMPPB]]|0.645|
|[[:human genes:d:dohh|DOHH]]|0.636|
|[[:human genes:a:alg1|ALG1]]|0.632|
|[[:human genes:g:gtf3c3|GTF3C3]]|0.63|
|[[:human genes:r:rnmt|RNMT]]|0.628|
|[[:human genes:t:triap1|TRIAP1]]|0.626|
|[[:human genes:g:gnb1l|GNB1L]]|0.618|
|[[:human genes:t:trmt5|TRMT5]]|0.615|
|[[:human genes:p:pmm2|PMM2]]|0.614|
|[[:human genes:r:rpp21|RPP21]]|0.613|
|[[:human genes:o:osgep|OSGEP]]|0.613|
|[[:human genes:a:atxn10|ATXN10]]|0.611|
|[[:human genes:a:adsl|ADSL]]|0.609|
|[[:human genes:n:nae1|NAE1]]|0.608|
|[[:human genes:t:tsen34|TSEN34]]|0.608|
|[[:human genes:t:tti2|TTI2]]|0.608|
|[[:human genes:d:dhps|DHPS]]|0.604|
|[[:human genes:s:srp14|SRP14]]|0.602|
|[[:human genes:e:eif4e|EIF4E]]|0.601|
|[[:human genes:p:polr3h|POLR3H]]|0.593|
|[[:human genes:y:yars|YARS]]|0.592|
|[[:human genes:e:exoc4|EXOC4]]|0.589|
|[[:human genes:c:ccdc101|CCDC101]]|0.589|
|[[:human genes:m:med16|MED16]]|0.588|
|[[:human genes:g:gtf3c2|GTF3C2]]|0.585|
|[[:human genes:u:uhrf1|UHRF1]]|0.581|
|[[:human genes:c:cct7|CCT7]]|0.572|
|[[:human genes:h:hspd1|HSPD1]]|0.569|
|[[:human genes:g:gtf3c4|GTF3C4]]|0.567|
|[[:human genes:a:alg14|ALG14]]|0.566|
|[[:human genes:a:aars|AARS]]|0.566|
|[[:human genes:a:alg2|ALG2]]|0.564|
|[[:human genes:a:alg13|ALG13]]|0.564|
|[[:human genes:p:pelo|PELO]]|0.561|
|[[:human genes:g:gtf3c6|GTF3C6]]|0.558|
|[[:human genes:p:ppp4c|PPP4C]]|0.558|
|[[:human genes:d:ddx1|DDX1]]|0.552|
|[[:human genes:v:vrk1|VRK1]]|0.551|
|[[:human genes:d:ddx20|DDX20]]|0.551|
|[[:human genes:t:tprkb|TPRKB]]|0.545|
|[[:human genes:p:ppcs|PPCS]]|0.544|
|[[:human genes:t:telo2|TELO2]]|0.54|
|[[:human genes:c:csnk2b|CSNK2B]]|0.538|
|[[:human genes:r:rpe|RPE]]|0.536|
|[[:human genes:e:eny2|ENY2]]|0.534|
|[[:human genes:n:nars|NARS]]|0.532|
|[[:human genes:t:tbca|TBCA]]|0.532|
|[[:human genes:p:polr3b|POLR3B]]|0.529|
|[[:human genes:m:meaf6|MEAF6]]|0.529|
|[[:human genes:t:tti1|TTI1]]|0.529|
|[[:human genes:h:hars|HARS]]|0.527|
|[[:human genes:m:med4|MED4]]|0.526|
|[[:human genes:c:crcp|CRCP]]|0.524|
|[[:human genes:t:tsen54|TSEN54]]|0.523|
|[[:human genes:e:eprs|EPRS]]|0.52|
|[[:human genes:r:rabggtb|RABGGTB]]|0.519|
|[[:human genes:g:gemin8|GEMIN8]]|0.519|
|[[:human genes:v:vezt|VEZT]]|0.519|
|[[:human genes:t:tgs1|TGS1]]|0.518|
|[[:human genes:t:trnt1|TRNT1]]|0.517|
|[[:human genes:d:dolk|DOLK]]|0.517|
|[[:human genes:p:plaa|PLAA]]|0.516|
|[[:human genes:c:ctc1|CTC1]]|0.515|
|[[:human genes:m:mllt1|MLLT1]]|0.513|
|[[:human genes:z:zrsr2|ZRSR2]]|0.513|
|[[:human genes:e:elp3|ELP3]]|0.512|
|[[:human genes:t:ten1|TEN1]]|0.512|
|[[:human genes:a:atp5j|ATP5J]]|0.512|
|[[:human genes:d:ddx55|DDX55]]|0.511|
|[[:human genes:g:gemin5|GEMIN5]]|0.51|
|[[:human genes:a:alg5|ALG5]]|0.509|
|[[:human genes:d:dpf2|DPF2]]|0.508|
|[[:human genes:r:rft1|RFT1]]|0.507|
|[[:human genes:c:cmtr1|CMTR1]]|0.507|
|[[:human genes:o:oraov1|ORAOV1]]|0.506|
|[[:human genes:t:taz|TAZ]]|0.505|
|[[:human genes:g:gemin6|GEMIN6]]|0.503|
|[[:human genes:u:uxt|UXT]]|0.502|
|[[:human genes:u:utp23|UTP23]]|0.502|
|[[:human genes:d:dr1|DR1]]|0.5|
|[[:human genes:c:cep57|CEP57]]|0.5|
|[[:human genes:l:lsm11|LSM11]]|0.498|
|[[:human genes:r:rpn1|RPN1]]|0.496|
|[[:human genes:r:rbm14|RBM14]]|0.494|
|[[:human genes:h:haus8|HAUS8]]|0.493|
|[[:human genes:h:hccs|HCCS]]|0.491|
|[[:human genes:f:fnta|FNTA]]|0.491|
|[[:human genes:p:pam16|PAM16]]|0.491|
|[[:human genes:r:rad50|RAD50]]|0.49|
|[[:human genes:c:c15orf41|C15orf41]]|0.489|
|[[:human genes:d:ddost|DDOST]]|0.488|
|[[:human genes:d:dhx29|DHX29]]|0.486|
|[[:human genes:c:cbfb|CBFB]]|0.485|
|[[:human genes:t:tamm41|TAMM41]]|0.485|
|[[:human genes:w:wdr59|WDR59]]|0.485|
|[[:human genes:c:c14orf166|C14orf166]]|0.484|
|[[:human genes:t:tmem41b|TMEM41B]]|0.484|
|[[:human genes:u:ube2g2|UBE2G2]]|0.482|
|[[:human genes:s:ssb|SSB]]|0.481|
|[[:human genes:t:tbcb|TBCB]]|0.48|
|[[:human genes:s:srp68|SRP68]]|0.48|
|[[:human genes:b:bap1|BAP1]]|0.479|
|[[:human genes:s:seh1l|SEH1L]]|0.479|
|[[:human genes:n:nsmce1|NSMCE1]]|0.478|
|[[:human genes:p:ppa2|PPA2]]|0.478|
|[[:human genes:c:casp9|CASP9]]|0.478|
|[[:human genes:m:mars|MARS]]|0.477|
|[[:human genes:m:mtor|MTOR]]|0.476|
|[[:human genes:u:uba3|UBA3]]|0.473|
|[[:human genes:a:apaf1|APAF1]]|0.473|
|[[:human genes:w:wdr24|WDR24]]|0.473|
|[[:human genes:p:pyroxd1|PYROXD1]]|0.471|
|[[:human genes:d:dicer1|DICER1]]|0.47|
|[[:human genes:a:atp5b|ATP5B]]|0.47|
|[[:human genes:e:eno1|ENO1]]|0.47|
|[[:human genes:l:lamtor5|LAMTOR5]]|0.47|
|[[:human genes:v:vmp1|VMP1]]|0.469|
|[[:human genes:u:urm1|URM1]]|0.469|
|[[:human genes:d:dhdds|DHDDS]]|0.467|
|[[:human genes:c:ctdnep1|CTDNEP1]]|0.467|
|[[:human genes:m:mapk14|MAPK14]]|0.467|
|[[:human genes:v:vhl|VHL]]|0.466|
|[[:human genes:r:rad1|RAD1]]|0.466|
|[[:human genes:d:dad1|DAD1]]|0.465|
|[[:human genes:e:elp2|ELP2]]|0.465|
|[[:human genes:b:bub3|BUB3]]|0.464|
|[[:human genes:t:timm13|TIMM13]]|0.463|
|[[:human genes:p:pax5|PAX5]]|0.463|
|[[:human genes:s:snapc5|SNAPC5]]|0.462|
|[[:human genes:p:ppp6c|PPP6C]]|0.462|
|[[:human genes:e:exoc3|EXOC3]]|0.461|
|[[:human genes:o:otud5|OTUD5]]|0.458|
|[[:human genes:z:znf608|ZNF608]]|0.457|
|[[:human genes:s:slc25a26|SLC25A26]]|0.457|
|[[:human genes:f:fh|FH]]|0.456|
|[[:human genes:e:eef1e1|EEF1E1]]|0.455|
|[[:human genes:u:ube2k|UBE2K]]|0.455|
|[[:human genes:p:pik3r4|PIK3R4]]|0.454|
|[[:human genes:e:elac2|ELAC2]]|0.452|
|[[:human genes:s:srp72|SRP72]]|0.451|
|[[:human genes:s:spcs2|SPCS2]]|0.448|
|[[:human genes:t:ttc4|TTC4]]|0.448|
|[[:human genes:u:uba5|UBA5]]|0.446|
|[[:human genes:d:dctn6|DCTN6]]|0.445|
|[[:human genes:o:oip5|OIP5]]|0.444|
|[[:human genes:p:pggt1b|PGGT1B]]|0.444|
|[[:human genes:p:ppp2r3c|PPP2R3C]]|0.444|
|[[:human genes:g:gtf3c5|GTF3C5]]|0.443|
|[[:human genes:t:tsen2|TSEN2]]|0.443|
|[[:human genes:c:cars|CARS]]|0.44|
|[[:human genes:a:atp5o|ATP5O]]|0.439|
|[[:human genes:t:trmt10a|TRMT10A]]|0.439|
|[[:human genes:t:timm22|TIMM22]]|0.439|
|[[:human genes:s:slc35b1|SLC35B1]]|0.438|
|[[:human genes:s:supv3l1|SUPV3L1]]|0.437|
|[[:human genes:t:txnl4b|TXNL4B]]|0.436|
|[[:human genes:t:tbp|TBP]]|0.436|
|[[:human genes:e:eif1ax|EIF1AX]]|0.436|
|[[:human genes:f:faf2|FAF2]]|0.434|
|[[:human genes:w:wdr82|WDR82]]|0.434|
|[[:human genes:d:dctn5|DCTN5]]|0.433|
|[[:human genes:a:alg6|ALG6]]|0.433|
|[[:human genes:n:nbn|NBN]]|0.432|
|[[:human genes:t:thoc6|THOC6]]|0.432|
|[[:human genes:s:sec62|SEC62]]|0.431|
|[[:human genes:d:diablo|DIABLO]]|0.43|
|[[:human genes:a:atic|ATIC]]|0.43|
|[[:human genes:x:xrcc3|XRCC3]]|0.429|
|[[:human genes:t:tp53rk|TP53RK]]|0.426|
|[[:human genes:p:pdap1|PDAP1]]|0.425|
|[[:human genes:b:bak1|BAK1]]|0.424|
|[[:human genes:r:rpia|RPIA]]|0.424|
|[[:human genes:s:snf8|SNF8]]|0.423|
|[[:human genes:r:romo1|ROMO1]]|0.423|
|[[:human genes:n:nsd1|NSD1]]|0.423|
|[[:human genes:z:znf259|ZNF259]]|0.422|
|[[:human genes:m:mad2l1|MAD2L1]]|0.422|
|[[:human genes:e:eif3f|EIF3F]]|0.421|
|[[:human genes:n:nup50|NUP50]]|0.421|
|[[:human genes:w:wdr92|WDR92]]|0.42|
|[[:human genes:t:tkt|TKT]]|0.419|
|[[:human genes:n:naa20|NAA20]]|0.418|
|[[:human genes:s:srprb|SRPRB]]|0.417|
|[[:human genes:m:med23|MED23]]|0.416|
|[[:human genes:t:thoc3|THOC3]]|0.416|
|[[:human genes:l:lsmd1|LSMD1]]|0.415|
|[[:human genes:s:sec61g|SEC61G]]|0.415|
|[[:human genes:n:nhlrc2|NHLRC2]]|0.415|
|[[:human genes:a:actr10|ACTR10]]|0.414|
|[[:human genes:m:metap2|METAP2]]|0.414|
|[[:human genes:t:taf1a|TAF1A]]|0.413|
|[[:human genes:s:slc25a19|SLC25A19]]|0.412|
|[[:human genes:r:rfk|RFK]]|0.412|
|[[:human genes:a:aasdhppt|AASDHPPT]]|0.411|
|[[:human genes:c:chchd4|CHCHD4]]|0.411|
|[[:human genes:t:tmed10|TMED10]]|0.41|
|[[:human genes:l:lamtor4|LAMTOR4]]|0.41|
|[[:human genes:l:lsm10|LSM10]]|0.41|
|[[:human genes:g:gtf2a2|GTF2A2]]|0.408|
|[[:human genes:f:fbxw7|FBXW7]]|0.408|
|[[:human genes:t:tcf4|TCF4]]|0.408|
|[[:human genes:a:atp2a2|ATP2A2]]|0.407|
|[[:human genes:s:ssbp2|SSBP2]]|0.407|
|[[:human genes:u:ube2l3|UBE2L3]]|0.407|
|[[:human genes:t:tpk1|TPK1]]|0.404|
|[[:human genes:c:cinp|CINP]]|0.404|
|[[:human genes:c:crls1|CRLS1]]|0.404|
|[[:human genes:w:wdr1|WDR1]]|0.403|
|[[:human genes:a:atm|ATM]]|0.403|
|[[:human genes:s:sod1|SOD1]]|0.403|
|[[:human genes:w:wars|WARS]]|0.403|
|[[:human genes:c:ciao1|CIAO1]]|0.403|
|[[:human genes:s:srp19|SRP19]]|0.402|
|[[:human genes:s:sdha|SDHA]]|0.402|
|[[:human genes:a:atp5a1|ATP5A1]]|0.402|
|[[:human genes:c:ccdc115|CCDC115]]|0.402|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 422/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|14/28|
|blood|12/28|
|bone|13/26|
|breast|13/33|
|central nervous system|39/56|
|cervix|1/4|
|colorectal|9/17|
|esophagus|9/13|
|fibroblast|0/1|
|gastric|8/16|
|kidney|12/21|
|liver|12/20|
|lung|47/75|
|lymphocyte|6/16|
|ovary|15/26|
|pancreas|15/24|
|peripheral nervous system|8/16|
|plasma cell|5/15|
|prostate|0/1|
|skin|11/24|
|soft tissue|6/9|
|thyroid|2/2|
|upper aerodigestive|15/22|
|urinary tract|21/29|
|uterus|3/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 925
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.76 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='RTCB Expression in NALM6 Cells: 6.76'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>