TICRR [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= TICRR =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: TICRR
  * **<color #00a2e8>Official Name</color>**: TOPBP1 interacting checkpoint and replication regulator
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=90381|90381]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q7Z2Z1|Q7Z2Z1]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TICRR&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TICRR|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/613298|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre- initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. {ECO:0000269|PubMed:20116089}.

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|regulation of DNA-dependent DNA replication initiation|
|mitotic DNA replication checkpoint|
|formation of translation preinitiation complex|
|DNA replication checkpoint|
|mitotic G2/M transition checkpoint|
|cytoplasmic translational initiation|
|regulation of DNA-dependent DNA replication|
|cytoplasmic translation|
|negative regulation of G2/M transition of mitotic cell cycle|
|negative regulation of cell cycle G2/M phase transition|
|mitotic DNA integrity checkpoint|
|regulation of DNA replication|
|translational initiation|
|DNA integrity checkpoint|
|response to ionizing radiation|
|mitotic cell cycle checkpoint|
|cell cycle checkpoint|
|regulation of G2/M transition of mitotic cell cycle|
|regulation of cell cycle G2/M phase transition|
|negative regulation of mitotic cell cycle phase transition|
|DNA replication|
|negative regulation of cell cycle phase transition|
|ribonucleoprotein complex assembly|
|ribonucleoprotein complex subunit organization|
|negative regulation of mitotic cell cycle|
|negative regulation of cell cycle process|
|regulation of DNA metabolic process|
|translation|
|chromatin binding|
|peptide biosynthetic process|
|regulation of mitotic cell cycle phase transition|
|response to radiation|
|regulation of cell cycle phase transition|
|ribonucleoprotein complex biogenesis|
|DNA repair|
|amide biosynthetic process|
|peptide metabolic process|
|negative regulation of cell cycle|
|mitotic cell cycle process|
|regulation of mitotic cell cycle|
|mitotic cell cycle|
|DNA metabolic process|
|regulation of cell cycle process|
|cellular response to DNA damage stimulus|
|cellular amide metabolic process|
|cellular protein-containing complex assembly|
|cell cycle process|
|response to abiotic stimulus|
|regulation of cell cycle|
|cell cycle|
|organonitrogen compound biosynthetic process|
|protein-containing complex assembly|
|cellular nitrogen compound biosynthetic process|
|cellular response to stress|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|protein-containing complex subunit organization|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|-2.05|
|[[:results:exp208|Vinblastine 0.015μM R05 exp208]]|-1.87|
|[[:results:exp13|Chloramphenicol 20μM R00 exp13]]|1.7|
|[[:results:exp351|Dexamethasone 0.006μM R07 exp351]]|1.73|
|[[:results:exp413|THZ531 0.11 to 0.175μM on day4 R07 exp413]]|1.74|
|[[:results:exp159|Docetaxel 0.001 to 0.002μM on day4 R04 exp159]]|1.77|
|[[:results:exp363|GSK-J4 1-1.25μM to day4 R07 exp363]]|1.89|
|[[:results:exp480|ETC-159 50μM R08 exp480]]|1.93|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|1.95|
|[[:results:exp50|Nicotinamide 2000μM R01 exp50]]|1.95|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|2.04|
|[[:results:exp41|BI-2536 0.001μM R01 exp41]]|2.38|
|[[:results:exp40|2-Methoxyestradiol 0.2μM R01 exp40]]|2.77|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:tceb3c|TCEB3C]]|0.624|
|[[:human genes:p:polr2j3|POLR2J3]]|0.617|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.61|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.604|
|[[:human genes:v:vasn|VASN]]|0.581|
|[[:human genes:p:prim1|PRIM1]]|0.579|
|[[:human genes:t:tfip11|TFIP11]]|0.569|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.567|
|[[:human genes:c:chd4|CHD4]]|0.566|
|[[:human genes:c:copb1|COPB1]]|0.561|
|[[:human genes:c:cbwd3|CBWD3]]|0.559|
|[[:human genes:p:psma6|PSMA6]]|0.556|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.553|
|[[:human genes:a:ankle2|ANKLE2]]|0.553|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.55|
|[[:human genes:c:cdca3|CDCA3]]|0.546|
|[[:human genes:a:atp6ap2|ATP6AP2]]|0.543|
|[[:human genes:c:chaf1a|CHAF1A]]|0.543|
|[[:human genes:t:twistnb|TWISTNB]]|0.543|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.543|
|[[:human genes:o:orc6|ORC6]]|0.543|
|[[:human genes:c:c14orf93|C14orf93]]|0.541|
|[[:human genes:s:supt5h|SUPT5H]]|0.536|
|[[:human genes:p:psmb4|PSMB4]]|0.536|
|[[:human genes:c:cbwd5|CBWD5]]|0.531|
|[[:human genes:s:supt6h|SUPT6H]]|0.531|
|[[:human genes:r:rrn3|RRN3]]|0.527|
|[[:human genes:n:nupl1|NUPL1]]|0.525|
|[[:human genes:c:col2a1|COL2A1]]|0.525|
|[[:human genes:c:copg1|COPG1]]|0.523|
|[[:human genes:n:nup160|NUP160]]|0.523|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.522|
|[[:human genes:s:slc4a1|SLC4A1]]|0.521|
|[[:human genes:d:dock6|DOCK6]]|0.519|
|[[:human genes:z:znf655|ZNF655]]|0.518|
|[[:human genes:d:dtl|DTL]]|0.518|
|[[:human genes:c:cbwd6|CBWD6]]|0.515|
|[[:human genes:t:timeless|TIMELESS]]|0.514|
|[[:human genes:p:psmd3|PSMD3]]|0.512|
|[[:human genes:t:tyms|TYMS]]|0.51|
|[[:human genes:g:gar1|GAR1]]|0.507|
|[[:human genes:a:aqr|AQR]]|0.504|
|[[:human genes:c:cdc6|CDC6]]|0.504|
|[[:human genes:s:sart1|SART1]]|0.502|
|[[:human genes:o:orc1|ORC1]]|0.502|
|[[:human genes:n:npipb5|NPIPB5]]|0.501|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.501|
|[[:human genes:k:kctd17|KCTD17]]|0.499|
|[[:human genes:c:cdc73|CDC73]]|0.497|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.496|
|[[:human genes:i:ik|IK]]|0.496|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.495|
|[[:human genes:p:plk1|PLK1]]|0.495|
|[[:human genes:p:psmc5|PSMC5]]|0.495|
|[[:human genes:n:nol10|NOL10]]|0.495|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.494|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.494|
|[[:human genes:w:wdr75|WDR75]]|0.493|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.493|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.492|
|[[:human genes:c:cgb2|CGB2]]|0.491|
|[[:human genes:c:copa|COPA]]|0.49|
|[[:human genes:k:krt78|KRT78]]|0.49|
|[[:human genes:c:ccdc94|CCDC94]]|0.488|
|[[:human genes:p:psmc1|PSMC1]]|0.487|
|[[:human genes:g:golga6a|GOLGA6A]]|0.487|
|[[:human genes:g:gprin2|GPRIN2]]|0.487|
|[[:human genes:h:hnrnpc|HNRNPC]]|0.485|
|[[:human genes:c:cope|COPE]]|0.485|
|[[:human genes:w:wdr87|WDR87]]|0.484|
|[[:human genes:z:znf106|ZNF106]]|0.484|
|[[:human genes:g:gid4|GID4]]|0.484|
|[[:human genes:p:psmb3|PSMB3]]|0.483|
|[[:human genes:e:exosc9|EXOSC9]]|0.483|
|[[:human genes:r:rad21|RAD21]]|0.482|
|[[:human genes:r:riok2|RIOK2]]|0.48|
|[[:human genes:a:aamp|AAMP]]|0.48|
|[[:human genes:p:pola2|POLA2]]|0.479|
|[[:human genes:c:ccna2|CCNA2]]|0.478|
|[[:human genes:c:cep192|CEP192]]|0.478|
|[[:human genes:p:psmb2|PSMB2]]|0.476|
|[[:human genes:m:med14|MED14]]|0.476|
|[[:human genes:s:sf3a1|SF3A1]]|0.476|
|[[:human genes:a:arcn1|ARCN1]]|0.476|
|[[:human genes:p:pole|POLE]]|0.476|
|[[:human genes:s:slc6a17|SLC6A17]]|0.475|
|[[:human genes:d:ddtl|DDTL]]|0.475|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.474|
|[[:human genes:r:rpl6|RPL6]]|0.473|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.473|
|[[:human genes:p:psmc2|PSMC2]]|0.471|
|[[:human genes:m:mphosph10|MPHOSPH10]]|0.471|
|[[:human genes:m:mt1e|MT1E]]|0.47|
|[[:human genes:r:rps2|RPS2]]|0.469|
|[[:human genes:r:rbm39|RBM39]]|0.469|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.467|
|[[:human genes:n:nbpf10|NBPF10]]|0.467|
|[[:human genes:n:nol12|NOL12]]|0.466|
|[[:human genes:n:nup153|NUP153]]|0.466|
|[[:human genes:p:pan3|PAN3]]|0.466|
|[[:human genes:r:rad51|RAD51]]|0.466|
|[[:human genes:d:dido1|DIDO1]]|0.465|
|[[:human genes:r:rpl35|RPL35]]|0.464|
|[[:human genes:a:acsf2|ACSF2]]|0.464|
|[[:human genes:p:polr1a|POLR1A]]|0.464|
|[[:human genes:z:znf830|ZNF830]]|0.463|
|[[:human genes:u:upf1|UPF1]]|0.462|
|[[:human genes:p:psmd8|PSMD8]]|0.462|
|[[:human genes:p:pigs|PIGS]]|0.461|
|[[:human genes:n:narfl|NARFL]]|0.461|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.459|
|[[:human genes:g:golga8o|GOLGA8O]]|0.459|
|[[:human genes:a:aatf|AATF]]|0.458|
|[[:human genes:n:nup43|NUP43]]|0.457|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.457|
|[[:human genes:f:fam160a1|FAM160A1]]|0.457|
|[[:human genes:s:sf3a3|SF3A3]]|0.457|
|[[:human genes:o:osbp|OSBP]]|0.456|
|[[:human genes:m:med17|MED17]]|0.455|
|[[:human genes:n:nol8|NOL8]]|0.453|
|[[:human genes:h:hivep3|HIVEP3]]|0.453|
|[[:human genes:n:npipb8|NPIPB8]]|0.453|
|[[:human genes:p:psmd7|PSMD7]]|0.452|
|[[:human genes:r:rrp15|RRP15]]|0.452|
|[[:human genes:m:myo1h|MYO1H]]|0.452|
|[[:human genes:s:ssh2|SSH2]]|0.452|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.452|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.452|
|[[:human genes:z:znf574|ZNF574]]|0.452|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.451|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.451|
|[[:human genes:r:rps12|RPS12]]|0.45|
|[[:human genes:p:psmb1|PSMB1]]|0.45|
|[[:human genes:m:mdn1|MDN1]]|0.45|
|[[:human genes:n:nsf|NSF]]|0.449|
|[[:human genes:i:iscu|ISCU]]|0.449|
|[[:human genes:o:or10g3|OR10G3]]|0.449|
|[[:human genes:e:exd1|EXD1]]|0.447|
|[[:human genes:r:rfxank|RFXANK]]|0.447|
|[[:human genes:p:pcf11|PCF11]]|0.447|
|[[:human genes:f:fbxo5|FBXO5]]|0.447|
|[[:human genes:s:smg7|SMG7]]|0.446|
|[[:human genes:s:snrpa1|SNRPA1]]|0.446|
|[[:human genes:s:stil|STIL]]|0.446|
|[[:human genes:r:rnf113a|RNF113A]]|0.446|
|[[:human genes:s:snip1|SNIP1]]|0.446|
|[[:human genes:f:fam231c|FAM231C]]|0.445|
|[[:human genes:g:gon4l|GON4L]]|0.445|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.444|
|[[:human genes:f:fam231a|FAM231A]]|0.444|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.444|
|[[:human genes:r:rpl34|RPL34]]|0.444|
|[[:human genes:p:psmd1|PSMD1]]|0.443|
|[[:human genes:p:paf1|PAF1]]|0.443|
|[[:human genes:r:rpl26|RPL26]]|0.441|
|[[:human genes:k:kpnb1|KPNB1]]|0.44|
|[[:human genes:c:cactin|CACTIN]]|0.44|
|[[:human genes:c:cdc45|CDC45]]|0.439|
|[[:human genes:n:napa|NAPA]]|0.439|
|[[:human genes:d:dhx38|DHX38]]|0.438|
|[[:human genes:a:akirin2|AKIRIN2]]|0.438|
|[[:human genes:v:vps54|VPS54]]|0.438|
|[[:human genes:t:tgfbrap1|TGFBRAP1]]|0.438|
|[[:human genes:s:sec13|SEC13]]|0.437|
|[[:human genes:p:ppm1d|PPM1D]]|0.437|
|[[:human genes:p:prpf19|PRPF19]]|0.437|
|[[:human genes:n:numa1|NUMA1]]|0.436|
|[[:human genes:r:rilpl2|RILPL2]]|0.435|
|[[:human genes:b:bysl|BYSL]]|0.434|
|[[:human genes:m:mbtd1|MBTD1]]|0.434|
|[[:human genes:c:ccdc116|CCDC116]]|0.434|
|[[:human genes:h:hap1|HAP1]]|0.434|
|[[:human genes:r:rpl3l|RPL3L]]|0.433|
|[[:human genes:z:zfand5|ZFAND5]]|0.433|
|[[:human genes:i:ints6|INTS6]]|0.433|
|[[:human genes:w:wdr43|WDR43]]|0.432|
|[[:human genes:n:nufip2|NUFIP2]]|0.432|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.432|
|[[:human genes:v:vps28|VPS28]]|0.432|
|[[:human genes:p:polr2d|POLR2D]]|0.432|
|[[:human genes:p:pola1|POLA1]]|0.432|
|[[:human genes:s:sap30bp|SAP30BP]]|0.431|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.431|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.431|
|[[:human genes:p:pan2|PAN2]]|0.431|
|[[:human genes:p:psmc6|PSMC6]]|0.431|
|[[:human genes:s:smg1|SMG1]]|0.431|
|[[:human genes:s:syt9|SYT9]]|0.431|
|[[:human genes:u:ubap1|UBAP1]]|0.43|
|[[:human genes:i:igfn1|IGFN1]]|0.43|
|[[:human genes:d:ddt|DDT]]|0.429|
|[[:human genes:r:rps5|RPS5]]|0.429|
|[[:human genes:c:cln6|CLN6]]|0.429|
|[[:human genes:p:ppfia4|PPFIA4]]|0.428|
|[[:human genes:m:myh2|MYH2]]|0.428|
|[[:human genes:c:cdh24|CDH24]]|0.428|
|[[:human genes:a:ankle1|ANKLE1]]|0.427|
|[[:human genes:s:strn|STRN]]|0.427|
|[[:human genes:r:rpl9|RPL9]]|0.427|
|[[:human genes:p:pwp2|PWP2]]|0.427|
|[[:human genes:r:rps7|RPS7]]|0.426|
|[[:human genes:c:copb2|COPB2]]|0.425|
|[[:human genes:t:traip|TRAIP]]|0.425|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.425|
|[[:human genes:r:rpl30|RPL30]]|0.425|
|[[:human genes:r:rbbp5|RBBP5]]|0.424|
|[[:human genes:u:utp3|UTP3]]|0.424|
|[[:human genes:p:psap|PSAP]]|0.423|
|[[:human genes:r:rrp7a|RRP7A]]|0.423|
|[[:human genes:d:dnm2|DNM2]]|0.423|
|[[:human genes:s:sult2b1|SULT2B1]]|0.423|
|[[:human genes:r:rps3a|RPS3A]]|0.422|
|[[:human genes:h:hist1h4b|HIST1H4B]]|0.421|
|[[:human genes:p:pno1|PNO1]]|0.42|
|[[:human genes:p:plxnb3|PLXNB3]]|0.42|
|[[:human genes:p:ppie|PPIE]]|0.419|
|[[:human genes:c:cwc22|CWC22]]|0.418|
|[[:human genes:p:psmd11|PSMD11]]|0.418|
|[[:human genes:t:tspy8|TSPY8]]|0.418|
|[[:human genes:f:fancm|FANCM]]|0.418|
|[[:human genes:f:fbxw9|FBXW9]]|0.418|
|[[:human genes:p:psmc4|PSMC4]]|0.417|
|[[:human genes:s:snrnp70|SNRNP70]]|0.417|
|[[:human genes:d:ddx47|DDX47]]|0.416|
|[[:human genes:h:hinfp|HINFP]]|0.416|
|[[:human genes:c:cmya5|CMYA5]]|0.416|
|[[:human genes:r:rpl10a|RPL10A]]|0.416|
|[[:human genes:s:sfpq|SFPQ]]|0.415|
|[[:human genes:e:exosc3|EXOSC3]]|0.413|
|[[:human genes:d:ddx21|DDX21]]|0.412|
|[[:human genes:p:pold1|POLD1]]|0.412|
|[[:human genes:f:fcn2|FCN2]]|0.412|
|[[:human genes:c:ctage4|CTAGE4]]|0.411|
|[[:human genes:c:copz1|COPZ1]]|0.41|
|[[:human genes:p:polr2j2|POLR2J2]]|0.41|
|[[:human genes:n:nckap1l|NCKAP1L]]|0.41|
|[[:human genes:n:ndc80|NDC80]]|0.41|
|[[:human genes:p:plk4|PLK4]]|0.409|
|[[:human genes:p:polr2h|POLR2H]]|0.409|
|[[:human genes:m:mtch2|MTCH2]]|0.408|
|[[:human genes:s:sprr2b|SPRR2B]]|0.407|
|[[:human genes:p:polr2j|POLR2J]]|0.407|
|[[:human genes:t:top1mt|TOP1MT]]|0.407|
|[[:human genes:d:disp2|DISP2]]|0.407|
|[[:human genes:p:psmd14|PSMD14]]|0.407|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.407|
|[[:human genes:i:ints5|INTS5]]|0.406|
|[[:human genes:c:cox8a|COX8A]]|0.406|
|[[:human genes:l:lrr1|LRR1]]|0.406|
|[[:human genes:m:mki67ip|MKI67IP]]|0.406|
|[[:human genes:n:nfatc4|NFATC4]]|0.405|
|[[:human genes:d:ddx41|DDX41]]|0.405|
|[[:human genes:r:rrm2|RRM2]]|0.405|
|[[:human genes:e:eif4a3|EIF4A3]]|0.404|
|[[:human genes:m:mdm2|MDM2]]|0.404|
|[[:human genes:b:bage|BAGE]]|0.404|
|[[:human genes:t:tuba8|TUBA8]]|0.404|
|[[:human genes:b:bage3|BAGE3]]|0.404|
|[[:human genes:p:psma1|PSMA1]]|0.403|
|[[:human genes:b:bage5|BAGE5]]|0.403|
|[[:human genes:b:bage4|BAGE4]]|0.403|
|[[:human genes:o:ogfr|OGFR]]|0.403|
|[[:human genes:b:bage2|BAGE2]]|0.403|
|[[:human genes:x:xylt2|XYLT2]]|0.401|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.401|
|[[:human genes:p:polr2a|POLR2A]]|0.401|
|[[:human genes:r:rangap1|RANGAP1]]|0.401|
|[[:human genes:c:chmp2a|CHMP2A]]|0.401|
|[[:human genes:s:s1pr4|S1PR4]]|0.401|
|[[:human genes:c:chchd3|CHCHD3]]|0.401|
|[[:human genes:m:mcf2l|MCF2L]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 602/726
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|1/1|
|bile duct|23/28|
|blood|23/28|
|bone|22/25|
|breast|26/33|
|central nervous system|46/56|
|cervix|3/4|
|colorectal|16/17|
|esophagus|7/13|
|fibroblast|1/1|
|gastric|12/15|
|kidney|16/21|
|liver|15/20|
|lung|63/75|
|lymphocyte|12/14|
|ovary|23/26|
|pancreas|22/24|
|peripheral nervous system|13/16|
|plasma cell|10/15|
|prostate|1/1|
|skin|18/24|
|soft tissue|7/7|
|thyroid|2/2|
|upper aerodigestive|19/22|
|urinary tract|23/29|
|uterus|5/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1468
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 7.51 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TICRR Expression in NALM6 Cells: 7.51'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>