ZNF720 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= ZNF720 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ZNF720
  * **<color #00a2e8>Official Name</color>**: zinc finger protein 720
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=124411|124411]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q7Z2F6|Q7Z2F6]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=ZNF720&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20ZNF720|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|KRAB|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|nucleic acid binding|
|DNA-binding transcription factor activity, RNA polymerase II-specific|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp11|CCCP 1μM R00 exp11]]|2.01|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 358/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|0/1|
|bile duct|19/28|
|blood|11/28|
|bone|11/26|
|breast|19/33|
|central nervous system|29/56|
|cervix|3/4|
|colorectal|9/17|
|esophagus|5/13|
|fibroblast|0/1|
|gastric|9/16|
|kidney|8/21|
|liver|9/20|
|lung|38/75|
|lymphocyte|5/16|
|ovary|14/26|
|pancreas|11/24|
|peripheral nervous system|6/16|
|plasma cell|8/15|
|prostate|1/1|
|skin|10/24|
|soft tissue|5/9|
|thyroid|0/2|
|upper aerodigestive|5/22|
|urinary tract|10/29|
|uterus|3/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 7509
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.92 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='ZNF720 Expression in NALM6 Cells: 4.92'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>