AGGF1
Gene Information
- Official Symbol: AGGF1
- Official Name: angiogenic factor with G-patch and FHA domains 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 55109
- UniProt: Q8N302
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010].
- UniProt Summary: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. {ECO:0000269|PubMed:14961121}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 19069
- Expression level (log2 read counts): 5.46
AGGF1 Expression in NALM6 Cells: 5.46
