Pfam Domains GO Terms
| Peptidase M14 |
| C-terminal protein deglutamylation |
| protein side chain deglutamylation |
| protein deglutamylation |
| cerebellar Purkinje cell differentiation |
| cerebellar Purkinje cell layer formation |
| cerebellar Purkinje cell layer morphogenesis |
| C-terminal protein amino acid modification |
| cell differentiation in hindbrain |
| cerebellar cortex formation |
| cerebellar Purkinje cell layer development |
| metallocarboxypeptidase activity |
| peptidyl-glutamic acid modification |
| cerebellar cortex morphogenesis |
| olfactory bulb development |
| olfactory lobe development |
| cerebellum morphogenesis |
| hindbrain morphogenesis |
| eye photoreceptor cell differentiation |
| cerebellar cortex development |
| tubulin binding |
| photoreceptor cell differentiation |
| cerebellum development |
| neuromuscular process |
| metencephalon development |
| eye morphogenesis |
| hindbrain development |
| central nervous system neuron differentiation |
| sensory organ morphogenesis |
| telencephalon development |
| eye development |
| visual system development |
| post-translational protein modification |
| sensory system development |
| forebrain development |
| mitochondrion organization |
| sensory organ development |
| intracellular membrane-bounded organelle |
| brain development |
| head development |
| zinc ion binding |
| nucleolus |
| peptidyl-amino acid modification |
| anatomical structure formation involved in morphogenesis |
| animal organ morphogenesis |
| central nervous system development |
| neuron differentiation |
| mitochondrion |
| proteolysis |
| nervous system process |
| generation of neurons |
| neurogenesis |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Phorbol-12-myristate-13-acetate 0.57μM R08 exp514 | 2.18 |
| AICAR 240μM R05 exp211 | 2.66 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution