CEACAM6
Gene Information
- Official Symbol: CEACAM6
- Official Name: CEA cell adhesion molecule 6
- Aliases and Previous Symbols: N/A
- Entrez ID: 4680
- UniProt: P40199
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| I-set |
| ig |
| V-set |
GO Terms
| positive regulation of endothelial cell-matrix adhesion via fibronectin |
| regulation of endothelial cell-matrix adhesion via fibronectin |
| positive regulation of heterotypic cell-cell adhesion |
| negative regulation of anoikis |
| regulation of anoikis |
| regulation of heterotypic cell-cell adhesion |
| heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| positive regulation of cell-matrix adhesion |
| azurophil granule membrane |
| anchored component of membrane |
| regulation of cell-matrix adhesion |
| positive regulation of cell-substrate adhesion |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| regulation of cell-substrate adhesion |
| positive regulation of cell-cell adhesion |
| cell-cell adhesion via plasma-membrane adhesion molecules |
| apical plasma membrane |
| leukocyte migration |
| regulation of cell-cell adhesion |
| positive regulation of cell adhesion |
| neutrophil degranulation |
| protein heterodimerization activity |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| positive regulation of cell migration |
| neutrophil activation |
| granulocyte activation |
| cell-cell adhesion |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| positive regulation of cell motility |
| positive regulation of cellular component movement |
| positive regulation of locomotion |
| myeloid leukocyte activation |
| cell surface |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| regulation of cell adhesion |
| regulated exocytosis |
| leukocyte mediated immunity |
| exocytosis |
| regulation of cell migration |
| negative regulation of apoptotic process |
| negative regulation of programmed cell death |
| regulation of cell motility |
| positive regulation of cell population proliferation |
| apoptotic process |
| leukocyte activation |
| cell adhesion |
| biological adhesion |
| cell migration |
| regulation of locomotion |
| negative regulation of cell death |
| regulation of cellular component movement |
| secretion by cell |
| export from cell |
| programmed cell death |
| identical protein binding |
| cell activation |
| localization of cell |
| cell motility |
| cell death |
| immune effector process |
| secretion |
| locomotion |
| regulation of apoptotic process |
| movement of cell or subcellular component |
| regulation of programmed cell death |
| extracellular space |
| regulation of cell population proliferation |
| regulation of cell death |
| immune response |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 7740
- Expression level (log2 read counts): -3.35
Expression Distribution
CEACAM6 Expression in NALM6 Cells: -3.35
