Pfam Domains GO Terms
| regulation of mitotic centrosome separation |
| pericentriolar material |
| regulation of centrosome cycle |
| spindle pole |
| microtubule organizing center |
| regulation of mitotic nuclear division |
| regulation of microtubule cytoskeleton organization |
| regulation of nuclear division |
| regulation of microtubule-based process |
| negative regulation of protein kinase activity |
| negative regulation of kinase activity |
| chromosome segregation |
| negative regulation of transferase activity |
| negative regulation of protein phosphorylation |
| negative regulation of phosphorylation |
| centrosome |
| regulation of cytoskeleton organization |
| negative regulation of phosphate metabolic process |
| negative regulation of phosphorus metabolic process |
| negative regulation of protein modification process |
| regulation of mitotic cell cycle |
| regulation of cell cycle process |
| negative regulation of catalytic activity |
| regulation of protein kinase activity |
| nucleolus |
| regulation of kinase activity |
| regulation of transferase activity |
| Golgi apparatus |
| negative regulation of cellular protein metabolic process |
| negative regulation of protein metabolic process |
| negative regulation of molecular function |
| regulation of cell cycle |
| mitochondrion |
| regulation of organelle organization |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Resveratrol 16μM R03 exp147 | 1.72 |
| Mdivi-1 15μM R05 exp217 | 2.17 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 1/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 1/21 |
| liver | 0/20 |
| lung | 1/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution