Pfam Domains GO Terms
| cartilage homeostasis |
| chondroitin sulfate proteoglycan biosynthetic process |
| chondroitin sulfate proteoglycan metabolic process |
| proteoglycan biosynthetic process |
| chondrocyte differentiation |
| proteoglycan metabolic process |
| cartilage development |
| tissue homeostasis |
| inner ear development |
| ear development |
| connective tissue development |
| positive regulation of DNA-binding transcription factor activity |
| glycoprotein biosynthetic process |
| multicellular organismal homeostasis |
| signaling receptor binding |
| anatomical structure homeostasis |
| glycoprotein metabolic process |
| regulation of DNA-binding transcription factor activity |
| skeletal system development |
| sensory organ development |
| carbohydrate derivative biosynthetic process |
| carbohydrate derivative metabolic process |
| positive regulation of transcription by RNA polymerase II |
| organonitrogen compound biosynthetic process |
| positive regulation of transcription, DNA-templated |
| extracellular space |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| homeostatic process |
| cellular macromolecule biosynthetic process |
| positive regulation of RNA metabolic process |
| tissue development |
| macromolecule biosynthetic process |
| positive regulation of molecular function |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| HMS-I1 10μM R06 exp256 | 1.7 |
| Ribavirin 10μM R01 exp52 | 1.84 |
| Alda-1 10μM R06 exp262 | 2.05 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution