Pfam Domains GO Terms
| DMA |
| DM |
| cerebral cortex regionalization |
| telencephalon regionalization |
| positive regulation of neuroblast proliferation |
| forebrain regionalization |
| dopaminergic neuron differentiation |
| regulation of neuroblast proliferation |
| neuron fate specification |
| positive regulation of stem cell proliferation |
| skeletal muscle cell differentiation |
| positive regulation of neural precursor cell proliferation |
| neuron fate commitment |
| regulation of stem cell proliferation |
| cell fate specification |
| regulation of neural precursor cell proliferation |
| cerebral cortex development |
| skeletal muscle tissue development |
| skeletal muscle organ development |
| pallium development |
| cell fate commitment |
| telencephalon development |
| striated muscle tissue development |
| muscle organ development |
| muscle tissue development |
| regionalization |
| forebrain development |
| sequence-specific DNA binding |
| pattern specification process |
| positive regulation of neurogenesis |
| muscle structure development |
| protein heterodimerization activity |
| positive regulation of nervous system development |
| positive regulation of cell development |
| brain development |
| head development |
| regulation of neurogenesis |
| protein homodimerization activity |
| positive regulation of cell population proliferation |
| regulation of nervous system development |
| regulation of cell development |
| positive regulation of cell differentiation |
| central nervous system development |
| neuron differentiation |
| positive regulation of developmental process |
| generation of neurons |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| regulation of cell population proliferation |
| neurogenesis |
| positive regulation of multicellular organismal process |
| tissue development |
| regulation of cell differentiation |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| A-196 10μM R03 exp114 | -2.23 |
| Epothilone-D 0.004 to 0.006μM on day4 R05 exp232 | -2.14 |
| UNC1999 2μM R03 exp155 | -1.8 |
| Asunaprenir 3μM R07 exp336 | -1.73 |
| A-395N 10μM R05 exp219 | -1.7 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 2/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution