DSCR3
Gene Information
- Official Symbol: VPS26C
- Official Name: VPS26 endosomal protein sorting factor C
- Aliases and Previous Symbols: N/A
- Entrez ID: 10311
- UniProt: O14972
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15230
- Expression level (log2 read counts): 5.61
DSCR3 Expression in NALM6 Cells: 5.61
