UniProt Summary: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
Pfam DomainsGO Terms
Pfam Domains
EGF
F5 F8 type C
GO Terms
extracellular vesicle
positive regulation of cell-substrate adhesion
integrin binding
extracellular matrix structural constituent
regulation of cell-substrate adhesion
collagen-containing extracellular matrix
positive regulation of cell adhesion
regulation of cell adhesion
calcium ion binding
cell adhesion
biological adhesion
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)