EIF4ENIF1

Official Symbol: EIF4ENIF1
Official Name: eukaryotic translation initiation factor 4E nuclear import factor 1
Aliases and Previous Symbols: N/A
Entrez ID: 56478
UniProt: Q9NRA8
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism. {ECO:0000269|PubMed:10856257}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UM0011500 10μM R05 exp246	-1.74
Artemisinin 50μM R08 exp450	1.92
Vemurafenib 6.6μM R08 exp434	1.96
Hippuristanol 0.12μM R08 exp489 no dilution day6	3.36
Hippuristanol 0.12μM R08 exp488	3.38
I-BRD9 4μM R07 exp365	3.45

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution