FAM173B
Gene Information
- Official Symbol: ATPSCKMT
- Official Name: ATP synthase c subunit lysine N-methyltransferase
- Aliases and Previous Symbols: N/A
- Entrez ID: 134145
- UniProt: Q6P4H8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| positive regulation of proton-transporting ATP synthase activity, rotational mechanism |
| regulation of mitochondrial ATP synthesis coupled proton transport |
| regulation of proton-transporting ATP synthase activity, rotational mechanism |
| mitochondrial crista |
| positive regulation of sensory perception of pain |
| regulation of ATP biosynthetic process |
| regulation of proton transport |
| protein-lysine N-methyltransferase activity |
| peptidyl-lysine trimethylation |
| regulation of oxidative phosphorylation |
| regulation of sensory perception of pain |
| regulation of purine nucleotide biosynthetic process |
| regulation of nucleotide biosynthetic process |
| regulation of sensory perception |
| positive regulation of nervous system process |
| peptidyl-lysine methylation |
| positive regulation of ion transmembrane transporter activity |
| positive regulation of transporter activity |
| regulation of purine nucleotide metabolic process |
| regulation of nucleotide metabolic process |
| regulation of ATP metabolic process |
| protein alkylation |
| protein methylation |
| regulation of nervous system process |
| positive regulation of cation transmembrane transport |
| positive regulation of ion transmembrane transport |
| regulation of generation of precursor metabolites and energy |
| positive regulation of transmembrane transport |
| macromolecule methylation |
| regulation of ion transmembrane transporter activity |
| regulation of transmembrane transporter activity |
| positive regulation of ion transport |
| regulation of transporter activity |
| methylation |
| peptidyl-lysine modification |
| regulation of cation transmembrane transport |
| regulation of intracellular transport |
| regulation of small molecule metabolic process |
| regulation of ion transmembrane transport |
| regulation of transmembrane transport |
| regulation of system process |
| regulation of ion transport |
| peptidyl-amino acid modification |
| regulation of cellular localization |
| positive regulation of transport |
| mitochondrion |
| regulation of phosphorylation |
| positive regulation of multicellular organismal process |
| positive regulation of molecular function |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| MS023 7μM R03 exp135 | -2.01 |
| Monensin 0.3μM R08 exp507 | 1.97 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 10867
- Expression level (log2 read counts): 4.43
Expression Distribution
FAM173B Expression in NALM6 Cells: 4.43
