GNGT2
Gene Information
- Official Symbol: GNGT2
- Official Name: G protein subunit gamma transducin 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 2793
- UniProt: O14610
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2010].
- UniProt Summary: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 9541
- Expression level (log2 read counts): 1.47
GNGT2 Expression in NALM6 Cells: 1.47
