Entrez Summary: Sequence analysis of this gene suggests that it is encodes a member of the superfamily of G protein-couple receptors. G protein-coupled receptors typically contain seven hydrophobic transmembrane domains, interact with guanine nucleotide binding regulatory proteins, and detect molecules outside the cell and act to transduce these signals into intracellular responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016].
UniProt Summary: Orphan receptor.
Pfam DomainsGO Terms
Pfam Domains
GPS
7tm 2
GO Terms
G protein-coupled receptor activity
G protein-coupled receptor signaling pathway
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)