UM0011500 5μM R05 exp245
Mechanism of Action
Unknown
- Class / Subclass 1: Uncharacterized Mechanism / Chemical Screen Hit
Technical Notes
Compound References
- PubChem Name: 3-(5,6-Dimethyl-1,3-dihydroisoindol-2-yl)-N-[(Z)-furan-2-ylmethylideneamino]benzamide
- Synonyms: N/A
- CAS #: 331431-73-3
- PubChem CID: 5440778
- IUPAC: 3-(5,6-dimethyl-1,3-dihydroisoindol-2-yl)-N-[(Z)-furan-2-ylmethylideneamino]benzamide
- INCHI Name: InChI=1S/C22H21N3O2/c1-15-9-18-13-25(14-19(18)10-16(15)2)20-6-3-5-17(11-20)22(26)24-23-12-21-7-4-8-27-21/h3-12H,13-14H2,1-2H3,(H,24,26)/b23-12-
- INCHI Key: GEVKZGPEQJGUIW-FMCGGJTJSA-N
- Molecular Weight: 359.42
- Canonical SMILES: CC1=CC2=C(CN(C2)C3=CC=CC(=C3)C(=O)NN=CC4=CC=CO4)C=C1C
- Isomeric SMILES: CC1=CC2=C(CN(C2)C3=CC=CC(=C3)C(=O)N/N=C\\C4=CC=CO4)C=C1C
- Molecular Formula: C22H21N3O2
Compound Supplier
- Supplier Name: Chem Bridge
- Catalog #: 5554888
- Lot #: Batch #01
Compound Characterization
- HRMS (ESI-TOF) m/z: [M+H]+ Calcd for C22H22N3O2 360.1707; found 360.1618
Dose Response Curve
- Platform ID: UM0011500
- Min: -8.2089; Max: 6.7698
| IC | Concentration (µM) |
|---|---|
| IC10 | N/A |
| IC20 | N/A |
| IC30 | N/A |
| IC40 | N/A |
| IC50 | N/A |
| IC60 | N/A |
| IC70 | N/A |
| IC80 | N/A |
| IC90 | N/A |
Screen Summary
- Round: 05
- Dose: 5µM
- Days of incubation: 8
- Doublings: 6.6
- Numbers of reads: 17275503
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 7/2 | Scores |
UM0011500 5μM R05 exp245
UM0011500 10μM R05 exp246 vs UM0011500 5μM R05 exp245
B02 10μM R08 exp453 vs UM0011500 5μM R05 exp245
CCT251545 0.2μM R06 exp271 vs UM0011500 5μM R05 exp245
