GYS2

Gene Information
  • Official Symbol: GYS2
  • Official Name: glycogen synthase 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 2998
  • UniProt: P54840
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. [provided by RefSeq, Dec 2009].
  • UniProt Summary: Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 16456
  • Expression level (log2 read counts): -1.01

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1