GYS2
Gene Information
- Official Symbol: GYS2
- Official Name: glycogen synthase 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 2998
- UniProt: P54840
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. [provided by RefSeq, Dec 2009].
- UniProt Summary: Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16456
- Expression level (log2 read counts): -1.01