GRIK1
Gene Information
- Official Symbol: GRIK1
- Official Name: glutamate ionotropic receptor kainate type subunit 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 2897
- UniProt: P39086
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11800
- Expression level (log2 read counts): -1.85
GRIK1 Expression in NALM6 Cells: -1.85
