HTR3E
Gene Information
- Official Symbol: HTR3E
- Official Name: 5-hydroxytryptamine receptor 3E
- Aliases and Previous Symbols: N/A
- Entrez ID: 285242
- UniProt: A5X5Y0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012].
- UniProt Summary: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8522
- Expression level (log2 read counts): -3.8
HTR3E Expression in NALM6 Cells: -3.8
