Pfam Domains GO Terms
| Interferon |
| type I interferon receptor binding |
| positive regulation of peptidyl-serine phosphorylation of STAT protein |
| regulation of peptidyl-serine phosphorylation of STAT protein |
| natural killer cell activation involved in immune response |
| B cell proliferation |
| response to exogenous dsRNA |
| response to dsRNA |
| natural killer cell activation |
| T cell activation involved in immune response |
| type I interferon signaling pathway |
| cellular response to type I interferon |
| response to type I interferon |
| lymphocyte proliferation |
| mononuclear cell proliferation |
| leukocyte proliferation |
| positive regulation of peptidyl-serine phosphorylation |
| B cell differentiation |
| lymphocyte activation involved in immune response |
| regulation of receptor signaling pathway via JAK-STAT |
| regulation of receptor signaling pathway via STAT |
| regulation of peptidyl-serine phosphorylation |
| B cell activation |
| cytokine activity |
| defense response to virus |
| T cell activation |
| lymphocyte differentiation |
| response to virus |
| blood coagulation |
| coagulation |
| hemostasis |
| leukocyte differentiation |
| humoral immune response |
| lymphocyte activation |
| wound healing |
| regulation of body fluid levels |
| cell population proliferation |
| hemopoiesis |
| response to wounding |
| hematopoietic or lymphoid organ development |
| adaptive immune response |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| immune system development |
| cytokine-mediated signaling pathway |
| innate immune response |
| response to organic cyclic compound |
| leukocyte activation |
| defense response to other organism |
| cellular response to cytokine stimulus |
| positive regulation of protein phosphorylation |
| positive regulation of phosphorylation |
| cell activation |
| response to nitrogen compound |
| immune effector process |
| response to cytokine |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| positive regulation of protein modification process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
| immune response |
| extracellular region |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| RRM1 | 0.441 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution