JRK

• Official Symbol: JRK
• Official Name: Jrk helix-turn-helix protein
• Aliases and Previous Symbols: N/A
• Entrez ID: 8629
• UniProt: O75564
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
• UniProt Summary: May bind DNA. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 8022
• Expression level (log2 read counts): 6.34

Expression Distribution

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JRK Expression in NALM6 Cells: 6.34