KRI1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
MLN-4924 2μM R00 exp22	-2.51
CCT251545 20μM R07 exp326	-2.3
Rotenone 2μM R00 exp33	-2.08
Radicicol 0.16μM R05 exp242	-2.01
Prochlorperazine 5.2μM R02 exp77	-1.91
Etoposide 10μM R00 exp20	-1.9
Talazoparib 0.006μM R06 exp299	-1.89
VER-155008 3.9μM R06 exp301	-1.87
Brefeldin A 0.02μM R00 exp8	-1.73
Etoposide 0.3μM R05 exp199	1.75
All-trans-Retinoic-Acid 40μM R07 exp334	1.86
Lapatinib 5μM R01 exp47	1.97
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	2.22

Global Fraction of Cell Lines Where Essential: 589/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	24/28
blood	22/28
bone	19/26
breast	25/33
central nervous system	39/56
cervix	3/4
colorectal	13/17
esophagus	9/13
fibroblast	1/1
gastric	11/16
kidney	19/21
liver	20/20
lung	64/75
lymphocyte	14/16
ovary	22/26
pancreas	21/24
peripheral nervous system	11/16
plasma cell	8/15
prostate	1/1
skin	19/24
soft tissue	7/9
thyroid	1/2
upper aerodigestive	18/22
urinary tract	21/29
uterus	3/5

Expression Distribution