UniProt Summary: Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. {ECO:0000269|PubMed:18443287}.
Pfam DomainsGO Terms
Pfam Domains
MBOAT
GO Terms
serine O-acyltransferase activity
protein octanoylation
peptidyl-serine octanoylation
O-acyltransferase activity
protein lipidation
lipoprotein biosynthetic process
integral component of endoplasmic reticulum membrane
lipoprotein metabolic process
protein acylation
peptidyl-serine modification
peptidyl-amino acid modification
endoplasmic reticulum membrane
organonitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)