NADK
Gene Information
- Official Symbol: N/ADK
- Official Name: N/AD kinase
- Aliases and Previous Symbols: N/A
- Entrez ID: 65220
- UniProt: O95544
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| NAD kinase |
GO Terms
| NADP biosynthetic process |
| NAD+ kinase activity |
| NADP metabolic process |
| pyridine nucleotide biosynthetic process |
| nicotinamide nucleotide biosynthetic process |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus |
| nicotinamide nucleotide metabolic process |
| pyridine nucleotide metabolic process |
| pyridine-containing compound biosynthetic process |
| pyridine-containing compound metabolic process |
| NAD metabolic process |
| oxidoreduction coenzyme metabolic process |
| regulation of insulin secretion involved in cellular response to glucose stimulus |
| positive regulation of insulin secretion |
| positive regulation of peptide hormone secretion |
| positive regulation of hormone secretion |
| coenzyme biosynthetic process |
| regulation of insulin secretion |
| ATP metabolic process |
| regulation of peptide hormone secretion |
| cofactor biosynthetic process |
| nucleotide biosynthetic process |
| nucleoside phosphate biosynthetic process |
| coenzyme metabolic process |
| regulation of hormone secretion |
| positive regulation of protein secretion |
| positive regulation of peptide secretion |
| positive regulation of secretion by cell |
| positive regulation of protein transport |
| positive regulation of secretion |
| cofactor metabolic process |
| nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| positive regulation of establishment of protein localization |
| regulation of protein secretion |
| regulation of peptide secretion |
| regulation of hormone levels |
| organophosphate biosynthetic process |
| nucleobase-containing small molecule metabolic process |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of secretion |
| organophosphate metabolic process |
| regulation of cellular localization |
| positive regulation of transport |
| regulation of protein localization |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| phosphorylation |
| organic cyclic compound biosynthetic process |
| organonitrogen compound biosynthetic process |
| ATP binding |
| cellular nitrogen compound biosynthetic process |
| small molecule metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 2159
- Expression level (log2 read counts): 7.6
Expression Distribution
NADK Expression in NALM6 Cells: 7.6
