UniProt Summary: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis. {ECO:0000269|PubMed:12852856, ECO:0000269|PubMed:16254247, ECO:0000269|PubMed:18538832}.
Pfam DomainsGO Terms
Pfam Domains
efhand
GO Terms
microtubule anchoring at centrosome
microtubule anchoring at microtubule organizing center
microtubule anchoring
intercellular bridge
ciliary basal body-plasma membrane docking
G2/M transition of mitotic cell cycle
cell cycle G2/M phase transition
organelle localization by membrane tethering
membrane docking
regulation of G2/M transition of mitotic cell cycle