NPY4R

Gene Information

Official Symbol: NPY4R
Official Name: neuropeptide Y receptor Y4
Aliases and Previous Symbols: N/A
Entrez ID: 5540
UniProt: P50391
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Bortezomib 0.05μM R00 exp7	-2
Actinomycin-D 0.001μM R00 exp3	-1.99
IU1-47 25μM R04 exp182	-1.77
Fluvastatin 2.2μM R06 exp282	1.74
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	2.29
Dexamethasone 0.006μM R07 exp351	2.53
Tunicamycin 0.04μM R07 exp418	2.63

Essentiality in NALM6

Essentiality Rank: 4713
Expression level (log2 read counts): -7.68

Expression Distribution