Entrez Summary: The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
NTF2
GO Terms
nuclear pore central transport channel
protein import into nucleus
import into nucleus
protein import
mRNA transport
protein localization to nucleus
nucleic acid transport
RNA transport
establishment of RNA localization
RNA localization
nucleobase-containing compound transport
nucleocytoplasmic transport
nuclear transport
establishment of protein localization to organelle
perinuclear region of cytoplasm
protein localization to organelle
intracellular protein transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)