OR56A5
Gene Information
- Official Symbol: OR56A5
- Official Name: olfactory receptor family 56 subfamily A member 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 390084
- UniProt: P0C7T3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Odorant receptor. {ECO:0000305}.
Pfam Domains GO Terms
Pfam Domains
| 7TM GPCR Srsx |
| 7tm 1 |
GO Terms
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway |
| dopamine binding |
| adrenergic receptor activity |
| synaptic transmission, dopaminergic |
| behavioral response to cocaine |
| adenylate cyclase-activating adrenergic receptor signaling pathway |
| adrenergic receptor signaling pathway |
| dopamine receptor signaling pathway |
| regulation of dopamine secretion |
| response to cocaine |
| regulation of catecholamine secretion |
| response to anesthetic |
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| cellular response to dopamine |
| response to dopamine |
| signal transduction involved in cellular response to ammonium ion |
| regulation of amine transport |
| regulation of response to drug |
| cellular response to monoamine stimulus |
| cellular response to catecholamine stimulus |
| response to catecholamine |
| response to monoamine |
| response to alkaloid |
| adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| cellular response to ammonium ion |
| adult behavior |
| cAMP-mediated signaling |
| cyclic-nucleotide-mediated signaling |
| response to ammonium ion |
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| response to xenobiotic stimulus |
| second-messenger-mediated signaling |
| cellular response to drug |
| chemical synaptic transmission |
| anterograde trans-synaptic signaling |
| trans-synaptic signaling |
| detection of chemical stimulus involved in sensory perception of smell |
| olfactory receptor activity |
| synaptic signaling |
| sensory perception of smell |
| detection of chemical stimulus involved in sensory perception |
| detection of chemical stimulus |
| sensory perception of chemical stimulus |
| cellular response to organic cyclic compound |
| detection of stimulus involved in sensory perception |
| behavior |
| cellular response to organonitrogen compound |
| cellular response to nitrogen compound |
| detection of stimulus |
| regulation of ion transport |
| regulation of secretion by cell |
| regulation of secretion |
| response to organic cyclic compound |
| sensory perception |
| response to organonitrogen compound |
| response to drug |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| cell-cell signaling |
| cellular response to endogenous stimulus |
| G protein-coupled receptor signaling pathway |
| nervous system process |
| integral component of plasma membrane |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| intracellular signal transduction |
| regulation of transport |
| system process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| LB-100 4.1μM R02 exp72 | -1.94 |
| Calcipotriol 5μM R08 exp464 | 1.71 |
| HMS-I1 1μM R01 exp46 | 2.07 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A
| Tissue | Fraction Of Cell Lines Where Essential |
|---|
Essentiality in NALM6
- Essentiality Rank: 11306
- Expression level (log2 read counts): -7.68
Expression Distribution
OR56A5 Expression in NALM6 Cells: -7.68
