PHF14
Gene Information
- Official Symbol: PHF14
- Official Name: PHD finger protein 14
- Aliases and Previous Symbols: N/A
- Entrez ID: 9678
- UniProt: O94880
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| PHD |
GO Terms
| regulation of mesenchymal cell proliferation involved in lung development |
| negative regulation of platelet-derived growth factor receptor-alpha signaling pathway |
| negative regulation of mesenchymal cell proliferation involved in lung development |
| regulation of platelet-derived growth factor receptor-alpha signaling pathway |
| negative regulation of mesenchymal cell proliferation |
| negative regulation of platelet-derived growth factor receptor signaling pathway |
| regulation of platelet-derived growth factor receptor signaling pathway |
| regulation of mesenchymal cell proliferation |
| lung alveolus development |
| lung development |
| respiratory tube development |
| respiratory system development |
| negative regulation of cell population proliferation |
| tube development |
| negative regulation of transcription by RNA polymerase II |
| negative regulation of developmental process |
| negative regulation of transcription, DNA-templated |
| negative regulation of multicellular organismal process |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of signal transduction |
| negative regulation of RNA metabolic process |
| negative regulation of cell communication |
| negative regulation of signaling |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| regulation of cell population proliferation |
| negative regulation of response to stimulus |
| negative regulation of gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 17807
- Expression level (log2 read counts): 6.67
Expression Distribution
PHF14 Expression in NALM6 Cells: 6.67
