Pfam Domains GO Terms
| MHC I |
| natural killer cell lectin-like receptor binding |
| susceptibility to natural killer cell mediated cytotoxicity |
| T cell mediated cytotoxicity |
| natural killer cell mediated cytotoxicity |
| natural killer cell mediated immunity |
| positive regulation of natural killer cell mediated cytotoxicity |
| positive regulation of natural killer cell mediated immunity |
| leukocyte mediated cytotoxicity |
| T cell mediated immunity |
| regulation of natural killer cell mediated cytotoxicity |
| regulation of natural killer cell mediated immunity |
| positive regulation of leukocyte mediated cytotoxicity |
| natural killer cell activation |
| positive regulation of cell killing |
| regulation of leukocyte mediated cytotoxicity |
| cell killing |
| regulation of cell killing |
| anchored component of membrane |
| positive regulation of lymphocyte mediated immunity |
| positive regulation of leukocyte mediated immunity |
| regulation of lymphocyte mediated immunity |
| regulation of leukocyte mediated immunity |
| positive regulation of immune effector process |
| lymphocyte mediated immunity |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
| positive regulation of innate immune response |
| positive regulation of response to biotic stimulus |
| lymphocyte activation |
| external side of plasma membrane |
| regulation of innate immune response |
| regulation of immune effector process |
| positive regulation of defense response |
| positive regulation of multi-organism process |
| regulation of response to biotic stimulus |
| positive regulation of response to external stimulus |
| adaptive immune response |
| viral process |
| regulation of defense response |
| innate immune response |
| leukocyte mediated immunity |
| regulation of multi-organism process |
| symbiotic process |
| interspecies interaction between organisms |
| positive regulation of immune response |
| leukocyte activation |
| defense response to other organism |
| endoplasmic reticulum |
| cell activation |
| immune effector process |
| regulation of response to external stimulus |
| regulation of immune response |
| positive regulation of immune system process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of response to stress |
| extracellular space |
| regulation of immune system process |
| immune response |
| extracellular region |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Quercetin 20μM R08 exp517 | -2.5 |
| Campthothecin 0.001μM R06 exp270 | -1.91 |
| Salubrinal 20μM R07 exp399 | -1.78 |
| Dimethyl-Sulfoxide 1pc R03 exp120 | 1.76 |
| NFN1 0.1μM R01 exp49 | 1.83 |
| THZ531 0.11μM R07 exp409 | 1.92 |
| Myriocin 25μM R06 exp293 | 1.99 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution