Pfam Domains GO Terms
| Rhomboid |
| negative regulation of natural killer cell activation |
| regulation of natural killer cell activation |
| regulation of acute inflammatory response |
| liver development |
| hepaticobiliary system development |
| negative regulation of lymphocyte activation |
| serine-type endopeptidase activity |
| negative regulation of leukocyte activation |
| negative regulation of cell activation |
| positive regulation of protein catabolic process |
| response to xenobiotic stimulus |
| regulation of inflammatory response |
| MAPK cascade |
| regulation of protein catabolic process |
| signal transduction by protein phosphorylation |
| gland development |
| positive regulation of catabolic process |
| negative regulation of immune system process |
| regulation of protein secretion |
| regulation of peptide secretion |
| regulation of lymphocyte activation |
| regulation of leukocyte activation |
| regulation of cell activation |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of defense response |
| regulation of secretion |
| protein phosphorylation |
| regulation of catabolic process |
| regulation of protein localization |
| regulation of response to external stimulus |
| proteolysis |
| phosphorylation |
| regulation of response to stress |
| regulation of immune system process |
| intracellular signal transduction |
| positive regulation of protein metabolic process |
| regulation of transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| CR131-b 0.005μM R08 exp474 | -2.29 |
| CCT251545 0.2μM R06 exp271 | 1.72 |
| Hypoxia 5%O2 R04 exp191 | 1.97 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution