Pfam Domains GO Terms
| regulation of AMPA glutamate receptor clustering |
| regulation of glutamate receptor clustering |
| asymmetric, glutamatergic, excitatory synapse |
| regulation of receptor clustering |
| regulation of postsynaptic neurotransmitter receptor activity |
| dendritic spine membrane |
| regulation of postsynaptic membrane organization |
| regulation of short-term neuronal synaptic plasticity |
| positive regulation of long-term synaptic potentiation |
| regulation of AMPA receptor activity |
| integral component of postsynaptic specialization membrane |
| AMPA glutamate receptor complex |
| ionotropic glutamate receptor binding |
| regulation of long-term synaptic potentiation |
| regulation of neuronal synaptic plasticity |
| regulation of glutamate receptor signaling pathway |
| regulation of neurotransmitter receptor activity |
| regulation of postsynapse organization |
| memory |
| regulation of nervous system process |
| positive regulation of synaptic transmission |
| regulation of cation channel activity |
| regulation of signaling receptor activity |
| regulation of protein localization to membrane |
| regulation of synaptic plasticity |
| postsynaptic membrane |
| regulation of synapse organization |
| regulation of synapse structure or activity |
| postsynaptic density |
| regulation of ion transmembrane transporter activity |
| learning or memory |
| regulation of transmembrane transporter activity |
| synapse |
| regulation of transporter activity |
| cognition |
| regulation of cation transmembrane transport |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| regulation of ion transmembrane transport |
| regulation of cellular protein localization |
| cell junction |
| regulation of transmembrane transport |
| behavior |
| regulation of system process |
| regulation of ion transport |
| regulation of cellular localization |
| regulation of protein localization |
| nervous system process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of transport |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| RRM1 | 0.439 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution