SLC25A15
Gene Information
- Official Symbol: SLC25A15
- Official Name: solute carrier family 25 member 15
- Aliases and Previous Symbols: N/A
- Entrez ID: 10166
- UniProt: Q9Y619
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.[provided by RefSeq, May 2009].
- UniProt Summary: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6376
- Expression level (log2 read counts): 4.34
SLC25A15 Expression in NALM6 Cells: 4.34
