UniProt Summary: In vitro, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space. Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane. {ECO:0000305|PubMed:26071602}.
Pfam DomainsGO Terms
Pfam Domains
PRELI
GO Terms
phosphatidic acid transfer activity
mitochondrial intermembrane space
phospholipid transport
organophosphate ester transport
lipid transport
lipid localization
organic anion transport
anion transport
ion transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)